DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9701 and LOC559107

DIOPT Version :9

Sequence 1:	NP_648918.1	Gene:	CG9701 / 39872	FlyBaseID:	FBgn0036659	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_021334699.1	Gene:	LOC559107 / 559107	-ID:	-	Length:	1900	Species:	Danio rerio

Alignment Length:	471	Identity:	209/471 - (44%)
Similarity:	291/471 - (61%)	Gaps:	14/471 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHPEKIVDRSNGDVSADSYHQWKRDVQMVK 90
            |...|:|...:::|||||.|.||.||.||||...|| ..||....|||::.|||::.:.|:..:|
Zfish  1344 FREGFVWSTATAAYQIEGAWRADGKGLSIWDKFAHT-SLKISQDENGDIACDSYNKIEEDIDNLK 1407

  Fly    91 ELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQELGG 155
            .|.|..||||:|||||:|.|....::.||:.||..|||.||..||.|.||:|||:|||.||::||
Zfish  1408 TLRVNHYRFSISWPRILPDGTNRKINEAGLNYYHRLIDVLLAANIKPQVTLYHWDLPQALQDVGG 1472

  Fly   156 WTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSYNY-PGIPAYLCGHN 219
            |.|..|:..|||||.:|....||:|:.|.|:|||::|...|:|....||...: ||...|:..||
Zfish  1473 WENDTIVDRFKDYADVVFNSLGDKVEFWITINEPYNVAMVGHGYGSAAPGITFRPGTAPYIVAHN 1537

  Fly   220 LLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREASERAMQFYVGWFGHPIFSK 284
            |:|||||..|:|.:.::.:.||.:|||:::.|.|||:|...||.:|:.|.:||.:|||.||:|
Zfish  1538 LIKAHAEAWHLYNDKYRAKHGGIVGITINSDWAEPRNPYKQEDVDAARRVVQFQLGWFAHPVF-- 1600

  Fly   285 HGNYPKVMIERIRNLSKEQGFGARSRLPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGK 349
            :|:|..:|.:.:|..|...|. .:|||||||.||:.||:||.|:||.|.||:.|..:..:.:
Zfish  1601 NGDYSDLMKDIVRERSLAAGL-PKSRLPEFTPEEVARIKGTHDYFGFNHYTTVLAYNFDYKD--- 1661

  Fly   350 FPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENGVSDRG-- 412
              :..::.|.||....:.. |..|||.||||.|.|...:|.:|..||....|.:||||||:||
Zfish  1662 --LQHYDADRGVGTVTDRT-WLDSGSFWLKVTPVGFRKILNFIKEEYGDHTIYITENGVSERGPV 1723

  Fly   413 GLEDYARVDYYNLYLSAVLDA-MEDGANISGYIAWSLMDSYEWKAGFSEKFGLYHVDFNSPQRTR 476
            .|.|..|:.||:.|::..|.| |.||.:|.||.||:|||:.||..||.::|||::|:.:.|...|
Zfish  1724 NLNDIPRIHYYDNYINQALKAYMLDGVDIRGYAAWTLMDNLEWATGFDDRFGLFYVNRSDPNLPR 1788

  Fly   477 TPKISARVFAQLCKTN 492
            .||.|...:|.:...|
Zfish  1789 IPKKSVWNYATIINCN 1804

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9701	NP_648918.1	Glyco_hydro_1	22..492	CDD:304882	208/469 (44%)
LOC559107	XP_021334699.1	Glyco_hydro_1	66..>164	CDD:329037
		Glyco_hydro_1	347..813	CDD:329037
		Glyco_hydro_1	865..1331	CDD:329037
		Glyco_hydro_1	1340..1806	CDD:329037	209/471 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592525
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2723
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257823at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10353
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940