DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9701 and Klb

DIOPT Version :9

Sequence 1:	NP_648918.1	Gene:	CG9701 / 39872	FlyBaseID:	FBgn0036659	Length:	541	Species:	Drosophila melanogaster
Sequence 2:	XP_038948671.1	Gene:	Klb / 289625	RGDID:	1308227	Length:	1043	Species:	Rattus norvegicus

Alignment Length:	489	Identity:	176/489 - (35%)
Similarity:	256/489 - (52%)	Gaps:	66/489 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SPVSQTR-----RFPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHPEKIVDRSNGDVSAD 77
            |||:..:     .||.:|.||||:.::|:||.|.||.:|.||||....:|...:   ::.|.|.|
  Rat    68 SPVNPGQLFLYDTFPKNFSWGVGTGAFQVEGSWKADGRGPSIWDRYVDSHLRGV---NSTDRSTD 129

  Fly    78 SYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIY 142
            ||...::|:..:..|.|..|:||:||||:.|.|.:..|:..|::||..|:|.|:..||.|:||:|
  Rat   130 SYVFLEKDLLALDFLGVSFYQFSISWPRLFPNGTVAAVNAKGLQYYRALLDSLVLRNIEPIVTLY 194

  Fly   143 HWELPQKLQ-ELGGWTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSY 206
            ||:||..|| |.|||.|..:|.||.|||....:.:|||||.|.|::.|:.|..||:|....||..
  Rat   195 HWDLPLTLQEEYGGWKNATMIDLFNDYATYCFQTFGDRVKYWITIHNPYLVAWHGFGTGMHAPGE 259

  Fly   207 NYPGIPAYLCGHNLLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREASERAMQ 271
            .......|..||||:|||::|.|.|.:.|:|.|.|.:.|||.:.|.||....:.||....:.:|.
  Rat   260 KGNLTAVYTVGHNLIKAHSKVWHNYDKNFRPHQKGWLSITLGSHWIEPNRTENMEDVINCQHSMS 324

  Fly   272 FYVGWFGHPIFSKHGNYPKVMIERIRNLSKEQGFGARSRLPEFTTEEIHRIRGTSDF----FGIN 332
            ..:|||.:||.. .|:||:.|             ...|.:|||:..|...:|||:||    ||.|
  Rat   325 SVLGWFANPIHG-DGDYPEFM-------------KTSSVIPEFSEAEKEEVRGTADFFAFSFGPN 375

  Fly   333 SY-TSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREY 396
            :: .||.|...|.|       .|.|                            :..:|.||..||
  Rat   376 NFRPSNTVVKMGQN-------VSLN----------------------------LRQVLNWIKLEY 405

  Fly   397 NAPEIIVTENG--VSDRGGLEDYARVDYYNLYLSAVLDAME-DGANISGYIAWSLMDSYEWKAGF 458
            :.|.|:::|||  .......||...:.....:|:.||.|:: |...:.||.||:|:|.:||:..:
  Rat   406 DNPRILISENGWFTDSYIKTEDTTAIYMMKNFLNQVLQAIKFDEIQVFGYTAWTLLDGFEWQDAY 470

  Fly   459 SEKFGLYHVDFNSPQRTRTPKISARVFAQLCKTN 492
            :.:.||::|||||.|:.|.||.||..:.|:.:.|
  Rat   471 TTRRGLFYVDFNSEQKERKPKSSAHYYKQIIQDN 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9701	NP_648918.1	Glyco_hydro_1	22..492	CDD:304882	172/483 (36%)
Klb	XP_038948671.1	Glyco_hydro	77..506	CDD:419968	173/480 (36%)
Klb	XP_038948671.1	Glyco_hydro	515..965	CDD:419968
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257823at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100193
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820