Protein Alignment CG9701 and KLB

DIOPT Version :9

• Sequence 1: NP_648918.1
• Gene: CG9701 / 39872
• FlyBaseID: FBgn0036659
• Length: 541
• Species: Drosophila melanogaster
• Sequence 2: NP_783864.1
• Gene: KLB / 152831
• HGNCID: 15527
• Length: 1044
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 183/513 - (35%)
• Similarity: 267/513 - (52%)
• Gaps: 69/513 - (13%)

  Fly     4 IILPLFVLTASCLG---------------SPVSQTR-----RFPNDFLWGVGSSSYQIEGGWNAD 48
            :||...:|..:..|               :||::::     .||.:|.||:|:.:.|:||.|..|
Human    39 VILSALILLRAVTGFSGDGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKD 103

  Fly    49 DKGESIWDFLTHTHPEKIVDRSNGDVSADSYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMN 113
            .||.||||...||| .|.|..:||  |:|||...::|:..:..:.|..|:||:||||:.|.|.:.
Human   104 GKGPSIWDHFIHTH-LKNVSSTNG--SSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVT 165

  Fly   114 HVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQE-LGGWTNPEIIPLFKDYARLVLEMYG 177
            ..:..|::|||.|:|.|:..||.|:||:|||:||..||| .|||.|..||.:|.|||....:|:|
Human   166 VANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFG 230

  Fly   178 DRVKIWTTVNEPWHVCEHGYGVDYMAPSYNYPGIPAYLCGHNLLKAHAEVVHMYRELFQPRQGGR 242
            ||||.|.|::.|:.|..||||....||.........|..||||:|||::|.|.|...|:|.|.|.
Human   231 DRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGW 295

  Fly   243 MGITLDTSWPEPRDPNSAEDREASERAMQFYVGWFGHPIFSKHGNYPKVMIERIRNLSKEQGFGA 307
            :.|||.:.|.||....:..|....:::|...:|||.:||.. .|:||:.|.:::.::
Human   296 LSITLGSHWIEPNRSENTMDIFKCQQSMVSVLGWFANPIHG-DGDYPEGMRKKLFSV-------- 351

  Fly   308 RSRLPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPG 372
               ||.|:..|.|.:|||:|||..:...:|....|.....|:      |..:.:.|:
Human   352 ---LPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQ------NVSLNLREA-------- 399

  Fly   373 SGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENG--VSDRGGLEDYARVDYYNLYLSAVLDAME 435
                            |.||..|||.|.|::.|||  ...|...||...:.....:||.||.|:.
Human   400 ----------------LNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIR 448

  Fly   436 -DGANISGYIAWSLMDSYEWKAGFSEKFGLYHVDFNSPQRTRTPKISARVFAQLCKTN 492
             |...:.||.||||:|.:||:..::.:.||::|||||.|:.|.||.||..:.|:.:.|
Human   449 LDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIREN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9701	NP_648918.1	Glyco_hydro_1	22..492	CDD:304882	176/478 (37%)
KLB	NP_783864.1	Glyco_hydro_1	77..508	CDD:304882	177/475 (37%)
		Glycosyl hydrolase-1 1	77..508		177/475 (37%)
		Glyco_hydro_1	517..967	CDD:304882
		Glycosyl hydrolase-1 2	517..967

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156854
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2723
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D257823at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100193
Panther	1	1.100	-	-	O	PTHR10353
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750