Protein Alignment Dbp73D and DBP6

DIOPT Version :9

• Sequence 1: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_014436.1
• Gene: DBP6 / 855774
• SGDID: S000005321
• Length: 629
• Species: Saccharomyces cerevisiae
• Alignment Length: 651
• Identity: 187/651 - (28%)
• Similarity: 294/651 - (45%)
• Gaps: 139/651 - (21%)

  Fly    43 KHEAIEVVETPILEKETSDVKESESKEE-----QVE---EPEKPLEVVQEEDVPSNEFQVL---- 95
            |.:|.|.........:.||...:.|.||     ||:   ..|...||.:||..||....||
Yeast    34 KRQATESDNEEYGSHQDSDESSNSSSEEDEDRMQVDYGASEEDSSEVEEEESKPSTHSTVLSRFK 98

  Fly    96 ---------------------GGDDSAAKKKKV-QMQLPNWLAHPTIIEGGSLQ-------PEEE 131
                                 |.:|.||...:: |:..|.::.:|..:...|||       ..|:
Yeast    99 QTVSLQERLGASDIAESKEDEGIEDEAASTHQLKQIPQPEFVKNPMNLNTNSLQFKSTGWLNTEK 163

  Fly   132 VPASEAI-----DQLDYLEKYTCQALKQMKIKRLFPVQKQVIPWILEA-----HAKPPPFRPR-- 184
            :....::     |..:.||....|.:.:......||:|..::..||..     :.....|..|
Yeast   164 IYYDNSLIKPFSDYANELEAKLLQNICKNFSTNTFPIQSIILDSILPVLNFTLNVSKRNFTRRIG 228

  Fly   185 DICVSAPTGSGKTLAFAIPIVQLLSQRVDCKVRALVVLPVAELALQVYRVISELCSKTELEVCLL 249
            ||.|:|.||||||||::|||||.|.:|...::|.::::|...|..|||..:::|...|.|.|.:.
Yeast   229 DILVNAATGSGKTLAYSIPIVQTLFKRQINRLRCIIIVPTKLLINQVYTTLTKLTQGTSLIVSIA 293

  Fly   250 SKQHKLEDEQEKLVEQYKGKYYSKADIVVTTPGRLVDHLHATKGFCLKSLKFLVIDEADRIMDAV 314
            ..::.|:||.:||..       .:.||::||||||||||: .|...||:||||:||||||:::..
Yeast   294 KLENSLKDEHKKLSN-------LEPDILITTPGRLVDHLN-MKSINLKNLKFLIIDEADRLLNQS 350

  Fly   315 FQNWLYHLDSHVKETTDQL--LAGTQAPLCYAELQASFGKQPHKLLFSATLSQDPEKLQDLRLFQ 377
            ||.|...|.||:|  ||:|  |.|...                |::|||||:.:.|||..|.|::
Yeast   351 FQGWCPKLMSHLK--TDKLDTLPGNVI----------------KMIFSATLTTNTEKLNGLNLYK 397

  Fly   378 PRLFATVLTMPVLKDATEEGADTEALTDPGQFVGRYTTPAELTE---QYCVTELRLKPLTVFALV 439
            |:||        ||       .|:.|         |..|.:|.|   .....:...|||.:...:
Yeast   398 PKLF--------LK-------QTDKL---------YQLPNKLNEFNINIPTAKSVYKPLILLYSI 438

  Fly   440 EKYK-----WKRFLCFTNSSDQATRLTFVLKVL------------FQKYSTKVSELSGNLSAKVR 487
            .::.     ..:.|.|..|::.:.||:.:|:::            .|..:..::.::.| ::|..
Yeast   439 CQFMAHSPIAAKILIFVKSNESSIRLSKLLQLICESRSQSSVLKNLQNLAVSINSVNSN-NSKAE 502

  Fly   488 NERL------RDFAAGKINGLICSDALARGIDVADVDVVLSYETPRHITTYIHRVGRTARAGRKG 546
            |:::      ...:|| |..||.:|.::||||:.|:..|::|:.|.....|:|||||||||...|
Yeast   503 NKKIVANFSHHSESAG-ITILITTDIMSRGIDINDITQVINYDPPMSSQQYVHRVGRTARANELG 566

  Fly   547 TAVTVLTEQ-DMTLFKKILSDANKGLGEEIHVSPDIEIQHA-VEYKEALAGLRSEKVKNKNQKMA 609
            :|..:|..: :.|.|    .|.||.|..:......:|:... :|....|.....|.:||.:...|
Yeast   567 SAYNLLVGRGERTFF----DDLNKDLDRDGKSVQPLELDFTLLESDSELYTSSLESLKNYHNNTA 627

  Fly   610 E 610
            :
Yeast   628 Q 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp73D	NP_476833.1	PRK11192	149..629	CDD:236877	154/499 (31%)
		DEAD	162..370	CDD:278688	84/216 (39%)
		HELICc	418..551	CDD:238034	41/158 (26%)
DBP6	NP_014436.1	SrmB	143..622	CDD:223587	160/534 (30%)
		DEADc_DDX51	185..402	CDD:350714	93/250 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346485
Domainoid	1	1.000	124	1.000	Domainoid score	I1198
eggNOG	1	0.900	-	-		E2759_KOG0350
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I939
Isobase	1	0.950	-	0	Normalized mean entropy	S2763
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005234
OrthoInspector	1	1.000	-	-		oto99122
orthoMCL	1	0.900	-	-		OOG6_103754
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R292
SonicParanoid	1	1.000	-	-		X3754
TreeFam	1	0.960	-	-
	13	12.730