Protein Alignment Dbp73D and ddx10

DIOPT Version :9

• Sequence 1: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: XP_001922220.1
• Gene: ddx10 / 569118
• ZFINID: ZDB-GENE-071022-2
• Length: 864
• Species: Danio rerio
• Alignment Length: 727
• Identity: 172/727 - (23%)
• Similarity: 280/727 - (38%)
• Gaps: 231/727 - (31%)

  Fly    14 KEQKDGAQGTNNEDEILQKLLKKAAKRKRKHEAIEVVETPILEKETSDVKESESKEEQVEEPEKP 78
            |:.|:....|::..:..:|..||.||.|.|                  ||.|:..:.:..:.|
Zfish     4 KKVKEKTNITDDPVKNFEKWKKKYAKTKTK------------------VKRSQKSKVKKRDWE-- 48

  Fly    79 LEVVQEEDVPSNEFQVLGGDDSAAKKKKVQMQLPNWLAHPTIIEGGSLQPEEEVPASEAIDQLDY 143
               |:.|::                ||.|...                   .|:...||:...|:
Zfish    49 ---VERENI----------------KKLVDKY-------------------SEINPKEAVKFSDF 75

  Fly   144 -LEKYTCQALKQMKIKRLFPVQKQVIPWILEAHAKPPPFRPRDICVSAPTGSGKTLAFAIPIVQL 207
             |.|.|.:.|.:.:.::...:|:|.|.:.|:.         ||:..:|.|||||||||.||:::.
Zfish    76 PLSKKTLKGLLEAQYRQPTEIQRQTIGFALQG---------RDVLGAAKTGSGKTLAFLIPVLEC 131

  Fly   208 LSQR----VDCKVRALVVLPVAELALQVYRVISELCSKTELEVCLLSKQHKLEDEQEKLVEQYKG 268
            |.:.    :| .:.||::.|..|||.|.:.|:.::....|....|:.....|:||.||:
Zfish   132 LYREQWTAMD-GLGALIISPTRELAYQTFEVLRKVGKNHEFSAGLVIGGKDLKDESEKI------ 189

  Fly   269 KYYSKADIVVTTPGRLVDHLHATKGFCLKSLKFLVIDEADRIMDAVFQNWLYHLDSHVKETTDQL 333
               .:.:|::.|||||:.|:..|..|....|..||:||||||:|..|              .|.|
Zfish   190 ---HRTNIIICTPGRLLQHMDETATFHASDLHMLVLDEADRILDMGF--------------ADTL 237

  Fly   334 LAGTQAPLCYAELQASFGKQPHKLLFSATLSQDPEKLQDLRLFQPRLFATVLTMPVLKDATEEGA 398
            .|          :..:..|....||||||.::..:.|..|
Zfish   238 NA----------IVENLPKSRQTLLFSATQTRSVKDLARL------------------------- 267

  Fly   399 DTEALTDPGQFV-----GRYTTPAELTEQYCVTELRLKPLTVFALVEKYKWKRFLCFTNSSDQAT 458
               :|.|| ::|     .:::|||.|.:.|.|.||..|...:::.:..:..|:.:.|.....:
Zfish   268 ---SLKDP-EYVWVHEQAKFSTPATLEQNYVVCELHQKVNMLYSFLRSHLQKKIIVFFACCKE-- 326

  Fly   459 RLTFVLKVLFQKY-----STKVSELSGNLSAKVRNERLRDFAAGKINGLICSDALARGIDVADVD 518
                 ::.||:.:     ...|..|.|......|.|...||.......|..:|..|||:|...|:
Zfish   327 -----VQYLFRIFCRLRPGISVLALHGKQQQMKRVEVYNDFVRKTSAVLFATDIAARGLDFPAVN 386

  Fly   519 VVLSYETPRHITTYIHRVGRTARAGRKGTAVTVLTEQDMTLFKKILSDANKGLGEEIHVS--PDI 581
            .||.::.|....|||||||||||....|.|:.||           |....||:..::...  |..
Zfish   387 WVLQFDCPEDANTYIHRVGRTARYKEGGEALLVL-----------LPSEEKGMISQLQEKKVPIN 440

  Fly   582 EIQHAVEYKEALAGLRSEKVKNKNQKMAEKNRVATKALI--HKKQEETAT------VRPLTLMEK 638
            :||           :..||:.:..||:        :|.:  .|:|:|.|.      :|.:.||:.
Zfish   441 KIQ-----------VNPEKLMSVQQKL--------EAFLAQEKEQKERAQRCFVSYLRSVYLMKN 486

  Fly   639 ------LQIKANEI-----------------VQSSKKSSETKNSKT----------------KAD 664
                  ||:|..|.                 .|..::::...:|.|                :..
Zfish   487 KDVFDVLQLKLPEYAMSLGLAVAPRVRFLLKAQQQRRTAAQDDSSTAGHQSEDELQSFTAQLQQQ 551

  Fly   665 KTKYQPKETKKQ 676
            |||.:|.:::::
Zfish   552 KTKSEPSQSEEE 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp73D	NP_476833.1	PRK11192	149..629	CDD:236877	131/497 (26%)
		DEAD	162..370	CDD:278688	65/211 (31%)
		HELICc	418..551	CDD:238034	40/137 (29%)
ddx10	XP_001922220.1	DEADc	72..276	CDD:238167	75/275 (27%)
		DEXDc	90..275	CDD:214692	70/256 (27%)
		HELICc	289..419	CDD:238034	40/136 (29%)
		DUF4217	452..511	CDD:290667	14/66 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920