Protein Alignment Dbp73D and Ddx24

DIOPT Version :9

• Sequence 1: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_954550.1
• Gene: Ddx24 / 373065
• RGDID: 727929
• Length: 851
• Species: Rattus norvegicus
• Alignment Length: 849
• Identity: 186/849 - (21%)
• Similarity: 302/849 - (35%)
• Gaps: 302/849 - (35%)

  Fly     5 TVNRYTEDLKEQKDGAQGTNNEDEILQKLLKKAAKRKRKHEAIEVVETPILEKETSDVKESESKE 69
            |..|..:.:.|:::..:|.::..       ||..|.|::.:||.|.|....:.|.         |
  Rat    71 TKKRKAQAVSEEEEEEEGESSSP-------KKKIKLKKQRDAILVAEGSAAQDEC---------E 119

  Fly    70 EQVEEPEKPLEVVQEEDVPSNEFQVLGGDDSAA-------------KKK---------KVQMQLP 112
            .:..||....|:....|      |.:||..|.:             |||         ||..:..
  Rat   120 GKASEPGAQGEITVCSD------QKVGGATSESLAQTVPRKKKNKGKKKLDTFQSTAPKVPKKAK 178

  Fly   113 NWLAHPTIIEGGSLQPEEEVPASEAIDQLD-YLEKYTCQALKQMKIKRLFPVQKQVIPWILEAHA 176
            .|:            ||.:...::.....| ::.|...:||..:......|:|         |..
  Rat   179 TWM------------PEVQDQKADVSAWRDLFVPKAVLRALSFLGFSAPTPIQ---------ALT 222

  Fly   177 KPPPFRPR-DICVSAPTGSGKTLAFAIPIVQLL-------------------------------- 208
            ..|..|.: ||..:|.||||||||||||::..:
  Rat   223 LAPAIRDKLDILGAAETGSGKTLAFAIPMIHSVLQWHKMKAPPIPSSAGVPPRLGAAAHRGSPCK 287

  Fly   209 -----------------SQRVDCKVRA-------------------------------------- 218
                             :|..|..|:|
  Rat   288 DGAKSGVLPEEATIETEAQPSDSGVQATAKAGASAASAQAGLFCDDDAGEGPSSLVEEKQSKDRE 352

  Fly   219 --------------------------------LVVLPVAELALQVYRVISELCSKTELEVCLL-- 249
                                            ||:.|..|||:||.:.|..:...|.:...:|
  Rat   353 EKLDEEQAGKLKQELCDQIAVYKVHPRRPLLGLVLTPTRELAVQVRQHIDAVAKFTGINTAILVG 417

  Fly   250 --SKQHKLEDEQEKLVEQYKGKYYSKADIVVTTPGRLVD-----HLHATKGFCLKSLKFLVIDEA 307
              |.|     :|::::.::       .:||:.|||||.:     |.|.:.   |:.|:.||||||
  Rat   418 GMSTQ-----KQQRMLNRH-------PEIVIATPGRLWELIKEKHPHLSN---LRQLRCLVIDEA 467

  Fly   308 DRIMDAVFQNWLYHLDSHVKETTDQLLAGTQAPLCYAEL--QASFGKQPHKLLFSATLS---QDP 367
            ||:::          ..|..|.: |||          |:  .:.:......|:|||||:   |.|
  Rat   468 DRMVE----------KDHFAELS-QLL----------EMLNDSQYNPNRQTLVFSATLTLVHQAP 511

  Fly   368 ------------EKLQDLRLFQPRLFATVLTMPVLKDATEEGADTEALTDPGQFVGRYTTPAELT 420
                        :|...|.|...::  .:...|.:.|.|......|.||:              |
  Rat   512 ARILHKKHVKKMDKTAKLDLLMQKI--GMRGKPKVIDLTRNEGTVETLTE--------------T 560

  Fly   421 EQYCVTELRLKPLTVFALVEKYKWKRFLCFTNSSDQATRLTFVLKVLFQKYSTKVSELSGNLSAK 485
            :.:|.|:  .|.|.::..:.:|. .|.|.|.||.....||:.:||||    ......|...:..|
  Rat   561 KIHCETD--EKDLYLYYFLMQYP-GRSLVFANSISCIKRLSGLLKVL----DIMPLTLHACMHQK 618

  Fly   486 VRNERLRDFAAGKINGLICSDALARGIDVADVDVVLSYETPRHITTYIHRVGRTARAGRKGTAVT 550
            .|...|..||..:...|:.:|..|||:|:..|..|:.|:.||....||||.||||||..:|.::.
  Rat   619 QRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYIHRSGRTARATSEGLSLM 683

  Fly   551 VLTEQDMTLFKKILSDANKGLGEEIHVSPDIEIQHAVEYKEALAGLRS-EKVKNKNQKMAEKNRV 614
            ::..:|:..||||.....|  .|:|.:.| ::.::....||.:...|. ||.:.:|
  Rat   684 LIGPEDVINFKKIYKTLKK--DEDIPLFP-VQSKYMDMVKERIRLARQIEKAEYRN--------- 736

  Fly   615 ATKALIHKKQEETATVRPLTLMEKLQIKANEIVQSSKKSSETKNSKTKADKTKYQPKETKKQIIA 679
             .:|.:|....|.|..       .|:|:..|.:...          .|||:.:.:.::.:.:|:.
  Rat   737 -FQACLHNSWIEQAAA-------ALEIELEEEMYKG----------GKADQQEERRRQKQMKILK 783

  Fly   680 KQLK 683
            ::|:
  Rat   784 QELR 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp73D	NP_476833.1	PRK11192	149..629	CDD:236877	145/626 (23%)
		DEAD	162..370	CDD:278688	71/353 (20%)
		HELICc	418..551	CDD:238034	45/132 (34%)
Ddx24	NP_954550.1	SrmB	191..735	CDD:223587	143/614 (23%)
		P-loop_NTPase	194..505	CDD:304359	72/355 (20%)
		Helicase_C	567..675	CDD:278689	39/114 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010