Protein Alignment Dbp73D and Prp5

DIOPT Version :10

• Sequence 1: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_573020.2
• Gene: Prp5 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Alignment Length: 884
• Identity: 185/884 - (20%)
• Similarity: 295/884 - (33%)
• Gaps: 331/884 - (37%)

  Fly    35 KKAAKRKRKHEA--IEVVETPILEKETSDVKESE------SKEEQVEEPEKPLEVVQEEDVPSNE 91
            ||..|:|.:..|  :|:||.|.:.......||.|      ..|.:||  :||    |.|..|.:|
  Fly   314 KKEIKKKPEPVAAKMEIVEEPTVAAGEKTKKEPEQPHVGAKSEPEVE--DKP----QPEAEPEDE 372

  Fly    92 FQVLGGDDSAAKKKKVQMQLPNWLAHP-------TIIEGGSLQPEEEVPASEAIDQ----LDY-- 143
            ...|   |:..::...:|:..|...:|       .|:.|.:.:....:...|.|:|    |:|
  Fly   373 IDPL---DAYMQEVNNEMRRVNNFVNPPAKSQGVVILTGVAKKKTTTLKKGEVIEQNMDSLEYSS 434

  Fly   144 -----------------------------------------------------LEKY-------- 147
                                                                 :|||
  Fly   435 EDELEDIRDTAVNLAMKHRKELAKIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKYRSDLEGIQ 499

  Fly   148 --------------TC-------QALKQMKIKRLFPVQKQVIPWILEAHAKPPPFRPRDICVSAP 191
                          .|       :.|:::..::..|:|.|.||.|:..         ||:...|.
  Fly   500 VKGKGCPKPIKTWAQCGVSKKEMEVLRRLGFEKPTPIQCQAIPAIMSG---------RDLIGIAK 555

  Fly   192 TGSGKTLAFAIPIVQLLSQRVDCK----VRALVVLPVAELALQVYRVISELCSKTELE-VCLLSK 251
            |||||||||.:|:.:.:..:...:    ..|:::.|..||.:|:.:.|.:......|. ||:...
  Fly   556 TGSGKTLAFILPMFRHILDQPSMEDGDGAIAIIMAPTRELCMQIGKDIRKFSKSLGLRPVCVYGG 620

  Fly   252 QHKLEDEQEKLVEQYKGKYYSKADIVVTTPGRLVDHLHATKGFC--LKSLKFLVIDEADRIMDAV 314
                ....|::.|..:|     |:|:|.||||::|.|.|..|..  |:.:.::|:|||||:.|..
  Fly   621 ----TGISEQIAELKRG-----AEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMG 676

  Fly   315 FQNWLYHLDSHVKETTDQLLAGTQAPLCYAELQASFGKQPHK--LLFSATLSQDPEKLQDLRLFQ 377
            |:..:..:..:|:                          |.:  ::||||..:..|.|.
  Fly   677 FEPQVMRIIDNVR--------------------------PDRQTVMFSATFPRQMEALA------ 709

  Fly   378 PRLFATVLTMPVLKDATEEGADTEALTDPGQFVGRYTTPAELTEQYCVTELRLKPLTVFALVEKY 442
                ..:|..|:           |.:..     ||.....|:.:...:.....|...:..|:..|
  Fly   710 ----RRILKKPI-----------EVIVG-----GRSVVCKEVEQHVVILNDDAKFFKLLELLGIY 754

  Fly   443 KWK-RFLCFTNSSDQATRLTFVLKVLFQKYSTKVSELSGNLSAKVRNERLRDFAAGKINGLICSD 506
            :.. ..:.|.:..:.|   ..:|:.| .|.|.....|.|.:....|:..:.||.:||:..||.:.
  Fly   755 QEAGSIIVFVDKQENA---DILLRDL-MKASYPCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATS 815

  Fly   507 ALARGIDVADVDVVLSYETPRHITTYIHRVGRTARAGRKGTAVTVLT------------------ 553
            ..|||:||.|:.:|::|:.|.|...|:||.|||.|||:||:|.|.:|
  Fly   816 VAARGLDVKDLILVVNYDVPNHYEDYVHRCGRTGRAGKKGSAYTFITPEQSRYAGDIIRAMDLSG 880

  Fly   554 ---------------------------------------EQDMTLFK--KILSDANKGLG----- 572
                                                   ||:....|  |.|..|..||.
  Fly   881 TLIPAELQALWTEYKALQEAEGKTVHTGGGFSGKGFKFDEQEFNAAKESKKLQKAALGLADSDDE 945

  Fly   573 EEIHVSPDIEIQHAVEYKE----------------ALAGLRSEKVKNKNQKMAEKNRVATKALIH 621
            |:|....|.:|:.....|.                |.|...:..|...|..:|.....|..|...
  Fly   946 EDIEQDIDQQIEQIFAAKRTVKDTSAAATAAAAAAAAAAAAAAAVSGANPALASAAAQAAAAAAA 1010

  Fly   622 KKQEETATVRP-------------------LTLMEKLQIKANEIVQSSKKSSETKNS-------- 659
            ......|...|                   |.|.::|..|.|     |.|:.:||.|
  Fly  1011 ANIAIAAASAPAAAGGAPSVAMGGALSSDKLELAKRLASKIN-----SSKNLDTKGSVVTVEPMI 1070

  Fly   660 ---------------KTKAD--------KTKYQPKETKK 675
                           :|.|:        |..|||||.::
  Fly  1071 KGPHVTGAAATLLTARTVAEQMAAKLNNKLNYQPKEDEE 1109

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp73D	NP_476833.1	DEADc_DDX51	149..381	CDD:350714	61/247 (25%)
		SrmB	150..631	CDD:440279	129/570 (23%)
Prp5	NP_573020.2	Trypan_PARP	<291..383	CDD:368653	23/77 (30%)
		DEAD-like_helicase_N	454..899	CDD:475120	112/518 (22%)
		KH-I_DDX46	1121..1223	CDD:411901