Protein Alignment Dbp73D and ddx18

DIOPT Version :9

• Sequence 1: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_001003411.1
• Gene: ddx18 / 321127
• ZFINID: ZDB-GENE-030131-9685
• Length: 653
• Species: Danio rerio
• Alignment Length: 635
• Identity: 173/635 - (27%)
• Similarity: 270/635 - (42%)
• Gaps: 148/635 - (23%)

  Fly    13 LKEQKDGAQGTNNEDEILQKLLKKAAKRKRKHEAIEVVETPILEKETSDVKE-----------SE 66
            ::||:.......||..  ||..||  |:|||.:|..       |..||.||:           |.
Zfish    56 IEEQQQSVSDEVNETS--QKPKKK--KKKRKLDATG-------ESTTSSVKKAKKQSVDTTQASA 109

  Fly    67 SKEEQVEEPEKPLEVVQEEDVPSNEFQVLGGDDSAAKKKKVQMQLPNWLAHPTIIEGGSLQPEEE 131
            .:|||.||..  ||.|:..:..:||.:....:||    .:...|||:.|.       |:.:....
Zfish   110 GEEEQQEEGN--LETVKCPENGNNEKEGSAEEDS----DEDGPQLPSGLT-------GAFEDRSF 161

  Fly   132 VPASEAIDQLDYLEKYTCQALKQMKIKRLFPVQKQVIPWILEAHAKPPPFRPRDICVSAPTGSGK 196
            ...||.:.:      .|.:.:|:|....:..:|.:.|..:||.         ||:..:|.|||||
Zfish   162 ASLSEVVSE------NTLKGVKEMGFDTMTEIQHKTIRPLLEG---------RDVLAAAKTGSGK 211

  Fly   197 TLAFAIPIVQLLSQRVDCKVR--------ALVVLPVAELALQVYRVISELCSKTELEVCLLSKQH 253
            ||||.||.::|:     .|::        .:|:.|..|||:|.|.|:.||.:.......|:....
Zfish   212 TLAFLIPSIELI-----YKLKFMPRNGTGVIVLSPTRELAMQTYGVLKELMTHHVHTYGLIMGGS 271

  Fly   254 KLEDEQEKLVEQYKGKYYSKADIVVTTPGRLVDHLHATKGFCLKSLKFLVIDEADRIMDAVFQNW 318
            ....|.:||.        :..:|:|.|||||:|||..|.||..|:|:.|:|||||||::..|:..
Zfish   272 NRSAEAQKLA--------NGVNILVATPGRLLDHLQNTPGFMFKNLQCLIIDEADRILEVGFEEE 328

  Fly   319 LYHLDSHVKETTDQLLAGTQAPLCYAELQASFGKQPHKLLFSATLSQDPEKLQDLRLFQPRLFAT 383
            |..:   :|     ||.                |:...:|||||.::..|.|..:.|.:..|:..
Zfish   329 LKQI---IK-----LLP----------------KKRQSMLFSATQTRKVEDLARISLKKEPLYVG 369

  Fly   384 VLTMPVLKDATEEGADTEALTDPGQFVGRYTTPAELTEQYCVTELRLKPLTVFALVEKYKWKRFL 448
            |       |..::.|..|.| :.|..|             |.:|.|.  |.:|..::|.:.|:.:
Zfish   370 V-------DDNKDTATVEGL-EQGYVV-------------CPSEKRF--LLLFTFLKKNRKKKLM 411

  Fly   449 CFTNSSDQATRLTFVLKVLFQKYSTKVSELSGNLSAKVRNERLRDFAAGKINGLICSDALARGID 513
            .|. ||..:.:..:   .|.......|..:.|......|......|.......|:|:|..|||:|
Zfish   412 VFF-SSCMSVKFHY---ELLNYIDLPVMAIHGKQKQTKRTTTFFQFCNADSGILLCTDVAARGLD 472

  Fly   514 VADVDVVLSYETPRHITTYIHRVGRTARA--GRKGTAVTVLTEQDMTLFKKILSDANKGLGEEIH 576
            :.:||.::.::.|.....||||||||||.  || |.|:.:|..:::. |.:.|..|...|.|
Zfish   473 IPEVDWIVQFDPPDDPKEYIHRVGRTARGINGR-GHALLILRPEELG-FLRFLKQAKVPLSE--- 532

  Fly   577 VSPDIEIQHAVEYKEALAGLRSEKVKNKNQKMAEKNRVATKALIHKKQEE 626
                      .|:    :..:...::::..|:.|||     ..:||..:|
Zfish   533 ----------FEF----SWTKISDIQSQLDKLIEKN-----YYLHKSAQE 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp73D	NP_476833.1	PRK11192	149..629	CDD:236877	134/488 (27%)
		DEAD	162..370	CDD:278688	69/215 (32%)
		HELICc	418..551	CDD:238034	39/134 (29%)
ddx18	NP_001003411.1	SrmB	160..646	CDD:223587	137/507 (27%)
		DEADc	161..368	CDD:238167	77/258 (30%)
		HELICc	382..511	CDD:238034	42/149 (28%)
		DUF4217	543..601	CDD:290667	7/26 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920