Protein Alignment Dbp73D and Ddx51

DIOPT Version :10

• Sequence 1: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_001388096.1
• Gene: Ddx51 / 304570
• RGDID: 1309580
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 675
• Identity: 257/675 - (38%)
• Similarity: 344/675 - (50%)
• Gaps: 110/675 - (16%)

  Fly     1 MELFTVNRY----------TEDLKEQKDGAQGTNNEDEILQKLLKKAAKRKRKHEAIE----VVE 51
            |.||.:.||          ||        |:.......:|::|..:|.:|:::...:|    ..|
  Rat     1 MALFHIARYAGPEAAGLGDTE--------AEAGGRARVLLERLQNRAREREQRQPELESTGTAAE 57

  Fly    52 TPI--------------------------LEKETSDVKESESKE------EQVEEP-EKPLEVVQ 83
            .|:                          .:|...||.....:|      |..|:| |.|.|.||
  Rat    58 APVRRRRRPRRRRGVSGSVAEKPEAPRAKRQKVEDDVDAGRGEETPEELSESAEDPGESPQEDVQ 122

  Fly    84 EEDVPSNEFQVLGGDDSAAKK-KKVQMQLPNWLAHPTIIEGG---SLQPEEEVPASEAIDQLDYL 144
            ....|.   :|||  |.|.|| .|||..||.|||.|:.::..   .|.|.|::|  |....|.
  Rat   123 RPPAPG---RVLG--DFARKKVPKVQPFLPAWLAKPSCVKKSVTEDLTPIEDIP--EVHPDLQ-- 178

  Fly   145 EKYTCQALKQMK---IKRLFPVQKQVIPWILEAH-----AKPPPFRPRDICVSAPTGSGKTLAFA 201
                    ||::   |...||||..|||.:||:.     .....::|.|:||||||||||||||.
  Rat   179 --------KQLRANGISSYFPVQAAVIPALLESADNGFLVGRGGYQPSDLCVSAPTGSGKTLAFV 235

  Fly   202 IPIVQLLSQRVDCKVRALVVLPVAELALQVYRVISELCSKTELEVCLLSKQHKLEDEQEKLVEQY 266
            ||:||.|..||.|.:|||||||..|||.||.:|.:.....|.|.|.|::.|..|..|||.||::.
  Rat   236 IPVVQALLHRVVCHIRALVVLPTKELAQQVSKVFNIYTDTTPLRVALVTGQKSLAKEQESLVQKT 300

  Fly   267 KGKYYSKADIVVTTPGRLVDHLHATKGFCLKSLKFLVIDEADRIMDAVFQNWLYHLDSHVKETTD 331
            ...:...|||||.||||||||:..|.||.|:.|:||:||||||::|::.|:||..:.:....|.|
  Rat   301 ADGFCCLADIVVATPGRLVDHIDQTPGFSLQQLRFLIIDEADRMIDSMHQSWLPRVVAAAFYTED 365

  Fly   332 -----QLLAGTQAPLCYAELQASFGKQP-HKLLFSATLSQDPEKLQDLRLFQPRLFATVLTMPVL 390
                 .||..|| |...........:.| .||||||||:|:|||||.|.|:|||||:|.|.....
  Rat   366 PTGSCALLQRTQ-PQAVTAASTCIPQMPLQKLLFSATLTQNPEKLQRLGLYQPRLFSTRLGHQSP 429

  Fly   391 KDATEEGADTEALTDPGQFVGRYTTPAELTEQYCVTELRLKPLTVFALVEKYKWKRFLCFTNSSD 455
            :|..|...:          :|:||.|..||..|....|..|||.||.||....:.|.||||||.:
  Rat   430 RDTVEVDEN----------LGKYTFPVGLTHHYVPCRLSSKPLIVFHLVLGMNFSRALCFTNSRE 484

  Fly   456 QATRLTFVLKVLFQKYSTKVSELSGNLSAKVRNERLRDFAAGKINGLICSDALARGIDVADVDVV 520
            .:.|| |:|...|...|  |:|.|.......|.:.|:.|..|||..||.:||.||||||..|::|
  Rat   485 NSHRL-FLLAQAFGGVS--VAEFSSRYGPGQRKKILKQFEQGKIQLLISTDATARGIDVQGVELV 546

  Fly   521 LSYETPRHITTYIHRVGRTARAGRKGTAVTVLTEQDMTLFKKILSDANKGLGE-EIHVSPDIEIQ 584
            ::|:.|:::.||:||||||||||:.|.|.|:|.:.....|.:::|:|  |:.| ..|..|...:|
  Rat   547 INYDAPQYLRTYVHRVGRTARAGKTGQAFTLLLKVQERKFLQMVSEA--GVPELACHEVPRKLLQ 609

  Fly   585 HAV-EYKEALAGLRSEKVKNKNQKM 608
            ..| .|:.||:.|  ||...:.||:
  Rat   610 PLVARYETALSQL--EKTVKEEQKL 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp73D	NP_476833.1	DEADc_DDX51	149..381	CDD:350714	117/245 (48%)
		SrmB	150..631	CDD:440279	207/475 (44%)
Ddx51	NP_001388096.1	DEADc_DDX51	177..421	CDD:350714	119/254 (47%)
		SF2_C_DEAD	448..578	CDD:350174	62/132 (47%)