Protein Alignment Dbp73D and rde-12

DIOPT Version :9

• Sequence 1: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_001256533.1
• Gene: rde-12 / 179855
• WormBaseID: WBGene00010280
• Length: 959
• Species: Caenorhabditis elegans
• Alignment Length: 606
• Identity: 149/606 - (24%)
• Similarity: 245/606 - (40%)
• Gaps: 189/606 - (31%)

  Fly    60 SDVKESESKEEQVEEPEK--PL-----EVVQEE-------DVPSNEFQVLGGDDSAAKKKKVQ-- 108
            ||...||.....|..|..  |:     |:|:|.       ||         |.|.|.:.:..:
 Worm   321 SDGSNSEGVNAPVRAPRDWVPVTRDIDELVRETADRLADCDV---------GQDRAVEIRNAEKD 376

  Fly   109 MQLPNWL---AHPTIIEGGSLQPEEEVPASEAIDQLDYLEKYTCQALKQMKIKRLFPVQKQVIPW 170
            ::|.:|.   .||||:|                            .||::|...:..:|..:||.
 Worm   377 VRLTSWTNSGLHPTILE----------------------------TLKRIKYNNVRTIQGAMIPQ 413

  Fly   171 ILEAHAKPPPFRPRDICVSAPTGSGKTLAFAIPIVQLLSQRVDCKVR----------ALVVLPVA 225
            :|:.|         |:...|.|.:|||.||.:||:..: .|:|.:.|          ||::.|..
 Worm   414 VLDGH---------DVLGQAETSAGKTAAFGLPIIDKI-LRMDEETRNKARQDDGPLALILAPTR 468

  Fly   226 ELALQVYRVISELCSKTELEVCLLSKQHKLEDEQEKLVEQYKGKYYSKADIVVTTPGRLVDHLHA 290
            |||.|::..:...|..|::.|.|...|   .|....|.|...|     .||::.|.||::|
 Worm   469 ELAAQIHEALRTYCQNTDIIVLLSYGQ---SDRARSLNEIRNG-----CDILIGTCGRIMD---- 521

  Fly   291 TKGFCLKS------LKFLVIDEADRIMDAVFQNWLYHLDSHVKETTDQLLAGTQAPLCYAELQAS 349
               |.:||      |:|||.|||||::..:.::.|.||.:.:|:......|.|:
 Worm   522 ---FTVKSHISLLHLRFLVFDEADRLLQDMKKDPLGHLGAIIKDAGFMESAATR----------- 572

  Fly   350 FGKQPHKLLFSATLSQDPEKLQDLRLFQPRLFATVLTMPVLKDATEEGADTEALTDPGQ------ 408
                 ..::.|||.:                 |:|:|:          |:......|||
 Worm   573 -----QTIMTSATFN-----------------ASVMTV----------ANELMKRLPGQDEMIKI 605

  Fly   409 --FVGRYTTPAELTEQYC--VTELRLKPLTVFALVEKYKWKRFLCFTNSSDQ----ATRLTFVLK 465
              ..||.:....|....|  :.|...|...:.......|..:.:.|....||    |.:||
 Worm   606 VLANGRLSKRVNLEFFECKGLAEKNAKLREILKQNVNGKTLKTIIFVQKKDQCDACAAKLT---- 666

  Fly   466 VLFQKYSTKVSELSGNLSAKVRNERLRDFAAGKINGLICSDALARGIDVADVDVVLSYETP---- 526
                ........|.|:.|..:|.:.:.||.:.::|.|:.:|.|:|||||:|:|.|::::.|
 Worm   667 ----SGGMLAQTLHGDRSQDMREKLINDFKSNRVNLLVTTDLLSRGIDVSDLDRVINFDLPDGDP 727

  Fly   527 -RHITTYIHRVGRTARAGRK--GTAVTVL---TEQDMTLFKKILSDANKGLGEEIHVS---PDIE 582
             :...|:|||.|||.|.|||  |..|:.:   :::|..|..|::         |:.:|   ||::
 Worm   728 DQGADTFIHRAGRTGRTGRKENGLCVSFVDPQSDRDSLLAPKLV---------ELIISQNLPDLK 783

  Fly   583 IQHAVEYKEALAGLRSEKVKN 603
            :.   ::.:|:|  :|.:.|:
 Worm   784 VP---DFLDAMA--KSSRGKS 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp73D	NP_476833.1	PRK11192	149..629	CDD:236877	127/498 (26%)
		DEAD	162..370	CDD:278688	61/223 (27%)
		HELICc	418..551	CDD:238034	43/145 (30%)
rde-12	NP_001256533.1	PTZ00110	230..799	CDD:240273	148/604 (25%)
		P-loop_NTPase	382..594	CDD:304359	74/307 (24%)
		HELICc	628..755	CDD:238034	41/134 (31%)
		Nucleoporin_FG	<867..950	CDD:290362

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010