Protein Alignment Dbp73D and ZK686.2

DIOPT Version :9

• Sequence 1: NP_476833.1
• Gene: Dbp73D / 39871
• FlyBaseID: FBgn0004556
• Length: 687
• Species: Drosophila melanogaster
• Sequence 2: NP_498690.2
• Gene: ZK686.2 / 176088
• WormBaseID: WBGene00022792
• Length: 593
• Species: Caenorhabditis elegans
• Alignment Length: 663
• Identity: 183/663 - (27%)
• Similarity: 302/663 - (45%)
• Gaps: 94/663 - (14%)

  Fly    14 KEQKDGAQGTNNEDEI-------LQKLLKKAAKRKRKHEAI--EVVETPILEKETSDVKESESKE 69
            |.||:.:. |.|:|||       :::.:.:........|::  :|.| |:   ||.||::|.
 Worm     4 KNQKEDSD-TENDDEIEPANGDGIEQEMNRVTNGNEDDESVGNDVAE-PM---ETEDVEDSG--- 60

  Fly    70 EQVEEPEKPLEVVQEEDVPSNE---FQVLGGDDSAAKKKKVQMQLPNWLAHPTIIEGGSLQPEEE 131
                      ||..||...:.|   |:|||..:  .|..:......:|:.:.|     :.....:
 Worm    61 ----------EVEIEETAQNGEREIFKVLGKQE--MKNLEALKVTSSWVQNAT-----TFSATID 108

  Fly   132 VPASEAIDQLDYLEKYTCQALKQMKIKRLFPVQKQVIPWILEAHAKPPPFRPRDICVSAPTGSGK 196
            ...|:.:.|::..|..|..:    .|...||||..|:|.:......|||.||||:.::|||||||
 Worm   109 SSTSQKLSQIELPEHLTVPS----AISTWFPVQYAVLPSLFFEIRSPPPLRPRDVAIAAPTGSGK 169

  Fly   197 TLAFAIPIVQLLSQRVDCKVRALVVLPVAELALQVYRVISELCSKTEL-EVCLLSKQHKLEDEQE 260
            |:.:.:|::..:..:....::|::::||..|..|:.........::.: :|..||..:..|.|..
 Worm   170 TICYVLPVLAAVGSKPSKILQAVILVPVQTLVAQIVDEFKRWNDESGVAKVVSLSGANDFEKEAR 234

  Fly   261 KLVEQYKGKYYSKADIVVTTPGRLVDHLHA--TKGFCLKSLKFLVIDEADRIMDAVFQNWLYHLD 323
            :|..       ...:::|.||.|||.||.:  .....|..|:||::|||||:...:.:.||
 Worm   235 QLAS-------DPPNVIVATPARLVQHLTSKIPPPIDLSKLRFLIVDEADRMGKLMREEWL---- 288

  Fly   324 SHVKETTDQLLAGTQAPLCYAELQASFGKQPHKLLFSATLSQDPEKLQDLRLFQPRLFATVLTMP 388
                :..:.|..|.:...|..::... .:.|.|::.|||||:|.|:|....||:||||:.  |..
 Worm   289 ----DLVEFLCGGMERVACLKDIIRQ-RRAPQKIVLSATLSKDVEELHLWNLFKPRLFSA--TAV 346

  Fly   389 VLKDATEEGADTEALTDPGQFVGRYTTPAELTEQYCVTELRLKPLTVFALVEKYKWKRFLCFTNS 453
            .:||.      |..:.......||...|:.::.:..||:.:..||.|:..:.:.|:.|.|.|.|.
 Worm   347 SVKDI------TSGIPQVDHVSGRLALPSSISHRLVVTDPKFHPLAVYQQITRNKFNRTLIFVNE 405

  Fly   454 SDQATRLTFVLKVLFQKYSTKVSELSGNLSAKVRNERLRDFAAGKINGLICSDALARGIDVADVD 518
            ...:.||..|||.|. |...:|...:..|..|.|.:.|..|...:...|||||.||||.|:..||
 Worm   406 VSSSNRLAHVLKELC-KDQFEVDYFTAQLFGKRRYKMLEKFNKNENRVLICSDVLARGTDLNKVD 469

  Fly   519 VVLSYETPRHITTYIHRVGRTARAGRKGTAVTVLTEQDMTLFKKIL------SDANKGLGEEIHV 577
            .|::|..|.....::||.|||.|||:.|..::|..::...||.|:|      .|..:...||...
 Worm   470 CVINYNLPADDKLFVHRAGRTGRAGQDGYVISVGDKESKRLFVKMLKVTNLWGDTVEEQMEEYIF 534

  Fly   578 SPDIEIQHAVEYKEALAGLRSEKVKNKNQKMAEKNRVATKALIHKKQEETATVRPLTLMEKLQIK 642
            ..|::     .|.:||..|::  ..:...|.....::|.::....|::.    ||....||..:|
 Worm   535 EKDMD-----RYSKALESLKA--TVSSQAKTGGSRQIAKRSGFEAKRKS----RPNARGEKPWLK 588

  Fly   643 ANEIVQSSKKSSE 655
                    ||::|
 Worm   589 --------KKTTE 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dbp73D	NP_476833.1	PRK11192	149..629	CDD:236877	142/488 (29%)
		DEAD	162..370	CDD:278688	63/210 (30%)
		HELICc	418..551	CDD:238034	47/132 (36%)
ZK686.2	NP_498690.2	DEXDc	130..352	CDD:214692	75/245 (31%)
		DEAD	135..330	CDD:278688	63/210 (30%)
		HELICc	371..502	CDD:238034	47/131 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167205
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0350
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	206	1.000	Inparanoid score	I2420
Isobase	1	0.950	-	0	Normalized mean entropy	S2763
OMA	1	1.010	-	-		QHG55255
OrthoDB	1	1.010	-	-		D303117at33208
OrthoFinder	1	1.000	-	-		FOG0005234
OrthoInspector	1	1.000	-	-		oto19172
orthoMCL	1	0.900	-	-		OOG6_103754
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3754
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.720