DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGRP-SB1 and Pglyrp1

DIOPT Version :9

Sequence 1:	NP_648917.1	Gene:	PGRP-SB1 / 39870	FlyBaseID:	FBgn0043578	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_033428.1	Gene:	Pglyrp1 / 21946	MGIID:	1345092	Length:	182	Species:	Mus musculus

Alignment Length:	180	Identity:	70/180 - (38%)
Similarity:	110/180 - (61%)	Gaps:	2/180 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 AALVLCCLALSANALQIEPRSSWGAVSARSPSRISGAVDYVIIHHSDNPNGCSTSEQCKRMIKNI 75
            |..:|..|.|:.:...|.|||.|.|:.:...||:...|.||:|.|:.. :.|::.:.|::..:|:
Mouse     4 ACALLALLGLATSCSFIVPRSEWRALPSECSSRLGHPVRYVVISHTAG-SFCNSPDSCEQQARNV 67

  Fly    76 QSDHKGRRNFSDIGYNFIVAGDGKVYEGRGFGLQGSHS-PNYNRKSIGIVFIGNFERSAPSAQML 139
            |..||....:.|:.|||::..||.||||||:.::|.|: |.:|..||||.|:|||....|:.:.|
Mouse    68 QHYHKNELGWCDVAYNFLIGEDGHVYEGRGWNIKGDHTGPIWNPMSIGITFMGNFMDRVPAKRAL 132

  Fly   140 QNAKDLIELAKQRGYLKDNYTLFGHRQTKATSCPGDALYNEIKTWPHWRQ 189
            :.|.:|:|....||:|:.||.:.|||..::|..|||.||..|::|.|:|:
Mouse   133 RAALNLLECGVSRGFLRSNYEVKGHRDVQSTLSPGDQLYQVIQSWEHYRE 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-SB1	NP_648917.1	PGRP	25..167	CDD:128941	56/142 (39%)
Pglyrp1	NP_033428.1	PGRP	20..160	CDD:128941	56/140 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842394
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46811
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	1	1.000	-	-		FOG0000842
OrthoInspector	1	1.000	-	-		otm44042
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.820