DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PGRP-SB2 and Pglyrp4

DIOPT Version :9

Sequence 1:	NP_001261970.1	Gene:	PGRP-SB2 / 39869	FlyBaseID:	FBgn0043577	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	XP_038958226.1	Gene:	Pglyrp4 / 310611	RGDID:	1308520	Length:	384	Species:	Rattus norvegicus

Alignment Length:	201	Identity:	60/201 - (29%)
Similarity:	83/201 - (41%)	Gaps:	70/201 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KLQLALVLCGLTLALGQI-----------------VPRSSW------CPVPISPRMPRLMVPVRL 43
            |.|...|..||...||.|                 |.|..|      |    |.::.|   ||.:
  Rat    32 KPQTNQVSKGLQQLLGNISQFFEKDILGRDDAFIMVSRKGWGAEATGC----SSKLGR---PVDV 89

  Fly    44 IIIHHTVTAPCFNPHQCQLVLRQIRADHMRRKFRDIGYNFLIGGDGRIYEGLGFGIRGEHAPRYN 108
            ::|||.....|.|...|...||:::|.|:|..:.|:.||||:|.||::|||:|:.::|.|...||
  Rat    90 LVIHHVPGLECHNQTVCSQKLRELQAYHIRNHWCDVAYNFLVGDDGKVYEGVGWNVQGSHDQGYN 154

  Fly   109 SQSIGIAFIGNFQNAPGCPNPHPNRCAASPGFAQLFRGGSLPNEGHCLSGNTPSQRAQKVAKLAT 173
            :.|:|:||.|.                               .|||     :||    .||.||.
  Rat   155 NISLGVAFFGT-------------------------------QEGH-----SPS----PVALLAM 179

  Fly   174 KALGFH 179
            :||..|
  Rat   180 EALISH 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PGRP-SB2	NP_001261970.1	PGRP	18..>129	CDD:128941	41/133 (31%)
Pglyrp4	XP_038958226.1	PGRP	67..201	CDD:128941	52/166 (31%)
Pglyrp4	XP_038958226.1	PGRP	222..362	CDD:128941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345816
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1110472at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_126407
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750