Protein Alignment Dab and dab1b

DIOPT Version :9

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: XP_005171167.1
• Gene: dab1b / 678641
• ZFINID: ZDB-GENE-060421-7958
• Length: 520
• Species: Danio rerio
• Alignment Length: 684
• Identity: 165/684 - (24%)
• Similarity: 249/684 - (36%)
• Gaps: 229/684 - (33%)

  Fly    43 RFFGDGVQFKAKLIGILEVGEARGDRMCQEALQDLK---MAIRAAGEHKQRITIHVTIDGLRLRD 104
            |:.|||:::|||||||.:|...|||::||:::..||   .:.|:.|:|||||.:.|:..|:::.|
Zfish    43 RYRGDGIRYKAKLIGIDDVTATRGDKLCQDSMMKLKGIAASARSKGKHKQRIFLTVSFGGIKIYD 107

  Fly   105 EKTGDSLYHHPVHKISFIAQDMTDSRAFGYIFGSPDSGHRFFGIKTDKAASQVVLAMRDLFQVVF 169
            |::|...:||.||:||:||:|..|.|||||:.|. ...|:|..|||..||:.|:|.:||||.::.
Zfish   108 ERSGVLQHHHSVHEISYIAKDSRDHRAFGYVCGK-KGNHKFVAIKTSHAAAPVILDLRDLFTLIH 171

  Fly   170 ELKKKEIEMARQQIQGKSLHD-HSSQLASLSSLKSSGLGGM------GLGHSDLASGGISSGHAL 227
            ::|:      |::.:.||..: |..|:...:.|:......:      ..||..|      .||.
Zfish   172 DIKQ------REEAEKKSQKEKHCEQVIYQTILEDEVDDPVYQYIVFEAGHEPL------HGHQ- 223

  Fly   228 TLLGSSLSTTNGTSRLGVSLDVAKASGSAAKEVSPESVADLVDLEQELTSLQR-GISQMERITPN 291
                                             |.|||      .|..||.|: ||..:.:
Zfish   224 ---------------------------------SEESV------YQVPTSQQKDGIYDVPK---- 245

  Fly   292 EPTTSSTGGAGHPSLAKSASEDDPFGDSFIYVPSYSILPPPP----DSGRNRHKPPNKTPDAVTS 352
                       |..:| :.|:.|.||| ....|....:|..|    |.||.|.   ...|:..|.
Zfish   246 -----------HHLMA-NISQVDLFGD-MATPPDILSMPASPATTLDPGRRRR---FVRPELFTH 294

  Fly   353 LDAMLSPPPGTSSSHGSASAGLQAADNDDDNWLQELDQQNDVFDTSKVVSSSGLGSVLAMAPLAS 417
            ..     ||...:.:.:..| ||||     :|..:                        ..|:|.
Zfish   295 FS-----PPAVPTGYMTMGA-LQAA-----HWTPQ------------------------ATPMAF 324

  Fly   418 SESTATPTQQLTEVAAGSGPL--ADLDIGLSTALGNEEQTSTILSLDAFTDLDPLGTGRTRPYVD 480
            ...|..   .:.::..|..|:  ...::..|.|.|.::.        ||.....:|.| |.|
Zfish   325 GVQTPL---HMAQMLPGGQPVIWGQANLFHSPATGQQQW--------AFVPAQAVGLG-THP--- 374

  Fly   481 KKYFFQELKNPPKKLLKELSSGSQAGLGLGLSLGQLDGLFPEDSTTISTTTTTATNITAGNPQQN 545
                                          :|...|.||.|..|....:.          .|.:.
Zfish   375 ------------------------------ISAAVLQGLIPLASMRPQSC----------EPPET 399

  Fly   546 SANTLTSTASTAASLGQLLSTVALNPDPLPAPISIPTSIS--HSITPSAEL--KLLLGHVTNPPN 606
            |:|.: |......|.|   |..|:|.||....|:....|:  .:|.||.:.  :|.|..:|
Zfish   400 SSNFM-SPQHLVDSRG---SEHAINTDPHEEVITAEICINKQDTIEPSVDSCEELDLSQMT---- 456

  Fly   607 PTGHYYTTEPPTLNSLENPHPPADPVLLPRDTDPFSPTRKKSDPDPFQESDLFAKLDAFEFEAPP 671
                ..||||.|                     ..|.|...:.|||  |....|...:.|.....
Zfish   457 ----LQTTEPST---------------------SASATDSCATPDP--EKQTTADATSVEELQDS 494

  Fly   672 AVPAPSIPNLATETKANVFNGPLQVQLPPEKELQ 705
            :|..|.:...|.:.:.|          ||:...|
Zfish   495 SVSVPEVLEKAADAQIN----------PPDSSQQ 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926	61/140 (44%)
dab1b	XP_005171167.1	PTB_Dab	34..182	CDD:269926	62/145 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574067
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002247
OrthoInspector	1	1.000	-	-		otm25692
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11232
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940