Protein Alignment Dab and ldlrap1

DIOPT Version :10

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: NP_001017114.1
• Gene: ldlrap1 / 549868
• XenbaseID: XB-GENE-954261
• Length: 309
• Species: Xenopus tropicalis
• Alignment Length: 285
• Identity: 66/285 - (23%)
• Similarity: 113/285 - (39%)
• Gaps: 54/285 - (18%)

  Fly    21 TFGGGSGAAEETNYAKHRNDPGRFFG------DGVQFKAKLIGILEVGEARGDRMCQEALQDLKM 79
            ::|||          ||:..|..:..      :|:.|..|.:|:..|.:.:|:.:...|::.:..
 Frog    21 SWGGG----------KHKKLPENWTDTRETLLEGMSFHLKYLGMTLVEQPKGEELSATAVKRIVA 75

  Fly    80 AIRAAGEHKQRITIHVTIDGLRLRDEKTGDSLYHHPVHKISFIAQDMTDSRAFGYIFGSPDSG-- 142
            ..:|:|:..|::.:.|:..|:.|.|..:...:.:..:::||:...|....:.|.||..|..:.
 Frog    76 TAKASGKKLQKVILKVSPRGIILYDLASNQLIENVSIYRISYCTADKMHDKVFAYIAQSQQNETL 140

  Fly   143 --HRFFGIKTDKAASQVVLAMRDLFQVVFEL------KKKEIEMARQQIQGKSLHDHSSQLASLS 199
              |.|...|. |.|..|.|.:...|:|.||.      .|::.|.:....:|.| ...|...:|::
 Frog   141 ECHAFLCTKR-KMAQAVTLTVAQAFKVAFEFWQVSRENKEKREKSGSDGEGAS-SSQSDGSSSIT 203

  Fly   200 SLKSSGLGGMGLGHSDLASG----GISSGHALTLLGSSLSTTNGT-------------SRLGVS- 246
            |||:|....: |...|.|..    ..|..|...|...:.|..|..             |||..|
 Frog   204 SLKASASANL-LDLEDCAKAFDALNASDNHIEDLFRQNESNENNNIVWALDDGLDEAFSRLAESR 267

  Fly   247 -----LDVAKASGSAAKE--VSPES 264
                 ||:...:.....|  :||.|
 Frog   268 TNPQVLDIGLTANDLQSEECLSPSS 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926	37/161 (23%)
		PRK12727	542..>708	CDD:237182
ldlrap1	NP_001017114.1	PTB_LDLRAP-mammal-like	43..165	CDD:269981	28/122 (23%)