Protein Alignment Dab and C1orf226

DIOPT Version :10

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: NP_001078844.1
• Gene: C1orf226 / 400793
• HGNCID: 34351
• Length: 272
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 63/274 - (22%)
• Similarity: 94/274 - (34%)
• Gaps: 79/274 - (28%)

  Fly   238 NGTSRLGVSLDVAKASGSAAKEVSPESVADL-----------VDLEQELTSLQR--GISQMERIT 289
            |..:.|...|..:::....:|.|:|.| |.|           |...|.|.:|.:  |....:.:.
Human     4 NLNTALTPKLQASRSFPHLSKPVAPGS-APLGSGEPGGPGLWVGSSQHLKNLGKAMGAKVNDFLR 67

  Fly   290 PNEPTTSSTGGAGHPSLAKSASEDDPFG-----------DSFIYVPSYSILPPPPDSGRNRHKPP 343
            ..||  ||.|..|...:.|:|......|           :..:...::..|.|||...|.|
Human    68 RKEP--SSLGSVGVTEINKTAGAQLASGTDAAPEAWLEDERSVLQETFPRLDPPPPITRKR---- 126

  Fly   344 NKTPDAV-TSLDAMLSPPP-------GTSSSHGSASAGLQA------ADNDDDNWLQELDQQNDV 394
              ||.|: |:.|.::|..|       ||..|.|.|......      ||........|.:::..|
Human   127 --TPRALKTTQDMLISSQPVLSSLEYGTEPSPGQAQDSAPTAQPDVPADASQPEATMEREERGKV 189

  Fly   395 F------------------DTSKV-------VSSSGL----GSVLAMAPLASSES---TATPTQQ 427
            .                  |.||:       .||..|    |..|:::|::.:||   .:.|.|.
Human   190 LPNGEVSLSVPDLIHKDSQDESKLKMTECRRASSPSLIERNGFKLSLSPISLAESWEDGSPPPQA 254

  Fly   428 LTEVAAGSGPLADL 441
            .|......||..||
Human   255 RTSSLDNEGPHPDL 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926
		PRK12727	542..>708	CDD:237182
C1orf226	NP_001078844.1	DUF4628	1..272	CDD:464712	63/274 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..47		10/43 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	111..130		8/24 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..272		27/122 (22%)