Protein Alignment Dab and si:ch211-204c21.1

DIOPT Version :9

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: XP_001920879.3
• Gene: si:ch211-204c21.1 / 368323
• ZFINID: ZDB-GENE-030429-35
• Length: 668
• Species: Danio rerio
• Alignment Length: 702
• Identity: 186/702 - (26%)
• Similarity: 292/702 - (41%)
• Gaps: 187/702 - (26%)

  Fly    43 RFFGDGVQFKAKLIGILEVGEARGDRMCQEALQDLK---MAIRAAGEHKQRITIHVTIDGLRLRD 104
            ||.|:||::||||||:.:|.|||||:|.|:::..||   :|.|:.|:||||:.:::::.|:.:.|
Zfish    42 RFKGNGVRYKAKLIGVDDVPEARGDKMSQDSMMKLKGKAVAARSQGKHKQRVWVNISLSGITVTD 106

  Fly   105 EKTGDSLYHHPVHKISFIAQDMTDSRAFGYIFGSPDSGHRFFGIKTDKAASQVVLAMRDLFQVVF 169
            ||||.::..|.|:||||||:|:||||||||:.|: :..|:||.|||.:.|..:|:.::||||::|
Zfish   107 EKTGAAILEHAVNKISFIARDVTDSRAFGYVCGA-EGQHQFFAIKTAQQAEPLVIDLKDLFQLIF 170

  Fly   170 ELKKKEIEMARQQIQGKSLHDHSSQLASLSSLKSSGLGGMGLGHSDLASGGISSGHALTLLGSSL 234
            .:||||:|.:::....|.:.:                |..| .|:|
Zfish   171 NMKKKEVEGSKKDENNKVVEN----------------GSEG-SHND------------------- 199

  Fly   235 STTNGTSRLGVSLDVAKASGSAAKEVSPESVAD--LVDLEQELTSLQRGISQMERITPNEPTTSS 297
              ..|..:|.:..|:     |...:::..|..|  |:||..|:.|.|..:.       ..|.|||
Zfish   200 --RKGVEQLDLFGDM-----STPPDLNSPSSEDILLMDLSTEIDSNQNCVK-------GNPFTSS 250

  Fly   298 TGGAGHPSLAKSASEDDPFGDSFIYVPSYSILPPPPDSGRNRHKPPNKTPDAVTSLDAMLSPPPG 362
            .......||    :.::||      ....|..|.|      .|.|.:..|....|.|..:...|.
Zfish   251 CVSRAQSSL----TPENPF------TSQLSFFPTP------IHDPFSDDPFYKKSDDQSIRDDPA 299

  Fly   363 TSSSHGSASAGLQAADNDDDNWLQELDQQNDVFDTSKVVS--SSGLGSVLAMAPLASSEST---- 421
            ..|.:...:.|.:..|:|      .|.||.|......|:.  |:|...|...|    .|:|
Zfish   300 NHSPNSLFNGGPKNGDSD------YLGQQFDQLSNRTVIQALSNGQWPVDGRA----GETTNWTQ 354

  Fly   422 -ATPTQQLTEVAAGSG---PLAD-LDIGLSTALGNEEQTSTILSLDAFTDLDP---LGTGRTRPY 478
             ..|.|:  :...|:|   |..: :..|:....|..|::....:.|:.....|   :..||.|
Zfish   355 NTVPVQE--QNGHGNGMPNPFVEKMQNGVKHENGGTEESHVHQAKDSVIICPPPLNMKAGRGR-- 415

  Fly   479 VDKKYFFQELKNPPKKLLKELSSGSQAGLGLGLSLGQLDG-LFPEDSTTIS-------TTTTTAT 535
                   :.:|:|         |....|:...:|..|.:. ..|.:|.::|       ::|.|.|
Zfish   416 -------RSVKSP---------SNENLGMASFVSAEQSESPPPPPESCSVSSLFSRSPSSTDTLT 464

  Fly   536 NITAGNPQQNSANTLTST--------------------------ASTAASLGQLLSTVALN-PDP 573
            ::...:.|..|.::|.:.                          |:..|..|.  |||:.. |..
Zfish   465 DLEGLSLQAPSGSSLWNQPLASIFSVSQPFTQAPVFSSSPGSVWANAPAGFGS--STVSQQLPSW 527

  Fly   574 LPAPISIPTSISHSITPSAELKLLLGHVTNPPN----PTGHYYTTEPPTLNSLENPHPPADPVLL 634
            ..||:|..::.|.|..|:      ||   ||..    |.|...::.||    |..|.|.|... .
Zfish   528 SAAPVSNGSNGSWSPHPT------LG---NPFQSSVFPDGQQSSSPPP----LVPPRPVATKE-A 578

  Fly   635 PR-------DTDPFSPTRKKSDPDPFQESDLFAKLDAFEFEAPPAVPAPSIP 679
            |:       |.||.....|:...|.|::         |:...||.|||...|
Zfish   579 PKVDSNAFVDLDPLGEKEKRDIKDMFKD---------FQMAKPPNVPARKEP 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926	70/140 (50%)
si:ch211-204c21.1	XP_001920879.3	PTB_Dab	33..182	CDD:269926	70/140 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574062
Domainoid	1	1.000	124	1.000	Domainoid score	I5446
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002247
OrthoInspector	1	1.000	-	-		otm25692
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11232
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.030