Protein Alignment Dab and ced-6

DIOPT Version :9

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: NP_001246225.1
• Gene: ced-6 / 35971
• FlyBaseID: FBgn0029092
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 109/531 - (20%)
• Similarity: 193/531 - (36%)
• Gaps: 145/531 - (27%)

  Fly    20 STFGGGSG------AAEETNYAKHR--NDPGRFFGDGVQFKAKLIGILEVGEARGDRMCQEAL-- 74
            :|.|||:|      |..|....|..  :.|.:.......:..|..|.|.|.:.:|..:.:||:
  Fly    66 NTSGGGTGSNSNGDAKSEAKNGKRNWLHTPEQLISGHAVYLVKFFGNLSVDQPKGIEVVKEAIRK 130

  Fly    75 ----QDLKMAIRAAGEHKQRITIHVTIDGLRLRDEKTGDSLYHHPVHKISFIA------------ 123
                |.:|.|.....|..:::.|.::|.|:.:::.:|...|:..|::.||:.|
  Fly   131 LQFAQQMKKAETGTQEKFKKLEITISIKGVAIQEPRTHKILHQFPLYNISYCADEKGVKKFFSFI 195

  Fly   124 ------QDMTDSRAFGYIFGSPD------SGHRFFGIKTDKAASQVVLAMRDLFQVVF-----EL 171
                  ||.:|..:.|:..|:.|      ..|..|...::|.||.:.|.:...|.:.:     ..
  Fly   196 AKTVKTQDGSDPTSNGHANGNGDGSAKVEESHECFVFISNKLASDITLTIGQAFDLAYRKYMDST 260

  Fly   172 KKKEIEMARQQIQ--GKSLHDHSSQLASLSS-LKSSGLGGM--GLGHSDL--------------A 217
            :|..:..|:|||.  .::::.:..:|..:|: |..:.|..:  .||..|:              |
  Fly   261 EKTNLSKAQQQINHLQQTVNVYKERLREVSAKLPKAELDALLFNLGIKDILEAPTTEPQNGIEVA 325

  Fly   218 SGGISSGHA--LTLLGSSLSTTNGTSRLGVS--LDVAKASGSAAKEVSPESVADLVDLEQELTSL 278
            |..:|:|..  ..||..:.|||..|.....|  |.:.....:.:.::|....::    .|::..|
  Fly   326 SEALSNGKLDDDKLLIDTNSTTASTHSASPSSFLPIVPPRNNLSSQISIGGKSN----SQKMDEL 386

  Fly   279 QRGISQMERITPNEPTTSSTGGAGHPSLAKSASEDDPFGDSFIYVPSYSILPPPPDSGRNRHKPP 343
            ...........|....|...||.|..:::      :.||                      .:|.
  Fly   387 LLNSDSDSDFDPRADETQEIGGTGRSAIS------NMFG----------------------FEPA 423

  Fly   344 NKTPDAVTSLDAMLSPPPGTSSSHGSASAGLQAADNDDDNWLQELDQQNDVFDTSKVVSSSGLGS 408
            |                          |.|.....|::|:.||..:....:...:..::|||..|
  Fly   424 N--------------------------SFGQHLFSNNNDHKLQNNNSSLLITSNNNSINSSGFSS 462

  Fly   409 VLAMAP--LASSESTATPTQQLTEVAAGSGPLADLDI----------GLSTALGNEEQTSTILSL 461
            .|.:.|  ||.....|.| ::|..|..|:|...:.|:          |.:....|:      |:|
  Fly   463 ELNITPPLLAPPPKIAAP-RRLNSVTTGNGLNGNTDLFGSDPFELNNGPNIFKQNQ------LNL 520

  Fly   462 DAFT--DLDPL 470
            |.|:  .||||
  Fly   521 DDFSLESLDPL 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926	37/182 (20%)
ced-6	NP_001246225.1	PTB_CED-6	92..261	CDD:269971	34/168 (20%)
		AceK	233..>304	CDD:295079	14/70 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11232
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940