DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dab and Fam43b

DIOPT Version :9

Sequence 1:NP_001163455.2 Gene:Dab / 39866 FlyBaseID:FBgn0000414 Length:2360 Species:Drosophila melanogaster
Sequence 2:XP_006239356.1 Gene:Fam43b / 313650 RGDID:1560959 Length:330 Species:Rattus norvegicus


Alignment Length:334 Identity:66/334 - (19%)
Similarity:110/334 - (32%) Gaps:116/334 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    37 HRNDPGR---FFGDGVQFKAKLIGILEVGEARGDRMCQEALQDLKMAIRAAGEHKQRITI--HVT 96
            ::.||..   :.|:.|...||           ||....:|:..:.......|..|.::|:  |  
  Rat    66 NKEDPTYTVWYLGNAVTLHAK-----------GDGCTDDAVGRIWARCGPGGGTKMKLTLGPH-- 117

  Fly    97 IDGLRLR--DEKTGDSLYHHPVH-----KISFIAQDMTDSRAFGYIFGSPDSGHRFFGIKTDKAA 154
              |:|::  :..:|.|....|.|     :|::.|.|....|.|.:::             ..:|.
  Rat   118 --GIRMQPSERGSGGSGGRRPAHAYLLPRITYCAADGRHPRVFTWVY-------------RHQAR 167

  Fly   155 SQVVLAMRDLFQVVFELKKKEIEMARQQIQGKSLHD--HSSQLASLSSLK----SSGLGGMGLGH 213
            .:.|:           |:...:.:||.. :.:||..  |.:.||:.|..|    .|....:...|
  Rat   168 HKAVV-----------LRCHAVLLARAH-KARSLARLLHQTALAAFSDFKRLQRQSDARHVRQQH 220

  Fly   214 SDLASGGISSGHALTLLGSSLST-----------TNGTSRLGVSLDVAKASGSAAKEVSPESVAD 267
              |.:||.::......|...|:.           :.|..||           |:.:|...|..|:
  Rat   221 --LRAGGAAASVPRAPLRRLLNAKCAYRPPPGERSRGAPRL-----------SSIQEEDEEEDAE 272

  Fly   268 LVDLEQELTSLQRGISQMER----ITPNEPTTSSTGGAGHPSLAKSASEDDPFGDSFIYVPSYSI 328
                |::....:.|..|.||    ....|..|.|..||                      |:   
  Rat   273 ----EEDAQDSEGGALQRERPEVLSLARELRTCSLRGA----------------------PA--- 308

  Fly   329 LPPPPDSGR 337
             ||||...|
  Rat   309 -PPPPAQPR 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DabNP_001163455.2 PTB_Dab 35..181 CDD:269926 28/155 (18%)
Fam43bXP_006239356.1 PH-like 71..262 CDD:418428 45/243 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166334817
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.840

Return to query results.
Submit another query.