Protein Alignment Dab and Rabgap1l

DIOPT Version :9

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: XP_006250167.1
• Gene: Rabgap1l / 304914
• RGDID: 1304620
• Length: 1051
• Species: Rattus norvegicus
• Alignment Length: 449
• Identity: 88/449 - (19%)
• Similarity: 154/449 - (34%)
• Gaps: 150/449 - (33%)

  Fly    47 DGVQF-KAKLIGILEVGEARGDRMCQEALQDLKMAIRAAGEHKQRITIHV--TIDG-LRLRDEKT 107
            |.|.| |...:|.::|...|.:   .|||:.: ..:||:.::...:|::|  ..:| :|:.|:.:
  Rat   127 DSVLFNKLTYLGCMKVSSPRSE---GEALRAM-ATMRASSQYPFAVTLYVPNVPEGSVRIIDQSS 187

  Fly   108 GDSLYHHPVHKISFIAQ---DMTDSRAFGYI---FGSPDSGHRFFGIKTDKAASQVVLA------ 160
            ...:...|::|:.|.|:   ..|:|..|.:.   .||.:.....|..:..:|.|:::.:
  Rat   188 NVEIASFPIYKVLFCARGHDGTTESNCFAFTESSHGSEEFQIHVFSCEIKEAVSRILYSFCTAFK 252

  Fly   161 --------MRD-----------LFQVVFELK--------------------------KKEIEMAR 180
                    ::|           .|.|..|:|                          :|::.:..
  Rat   253 RSSRQVSDVKDSIIPTPDSDVFTFSVSLEVKEDDGKGNFSPVPKDRDKFYFKIKQGIEKKVVITV 317

  Fly   181 QQIQGKSL---HDHSSQLASLSSLKSSGLGGMGLGHSDLASGGIS-SGHALTLLGSSLSTTNGTS 241
            ||:..|.|   ......|:...::|:|.:..:     |:.|.|.| .|.|..:.|  :...|...
  Rat   318 QQLSNKELAIERCFGMLLSPGRNVKNSDMHLL-----DMESMGKSYDGRAYVITG--MWNPNAPI 375

  Fly   242 RLGVSLDVAKASGSAAKEVSPESVADLVDLEQELTSLQRGISQMERITP-NE-------PTTSST 298
            .|.::.:..|     .|.|......|:| :.:.:..::..:..:.|:.| ||       .|.:.|
  Rat   376 FLALNEETPK-----DKRVYMTVAVDMV-VTEVVEPVRFLLETVVRVYPANERFWYFSRKTFTET 434

  Fly   299 --------GGAGHPSLAKSASEDDPFGDSFIYVPSYSILPPPPDSGRNRHKPPNKTPDAVTSLDA 355
                    .|.||.|.          ||:...|.|..         |...|....||
  Rat   435 FFMRLKQSEGKGHSSA----------GDAIYEVVSLQ---------RESDKEEPVTP-------- 472

  Fly   356 MLSPPPGTSSSHGSASAGLQAADNDDDNWLQELDQQNDVFDTSKVVSSSGLGSVLAMAP 414
                    :|..|.||.....|:.:.||.|                 |||.|.|....|
  Rat   473 --------TSGGGPASPQEDEAEEESDNEL-----------------SSGTGDVSKDCP 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926	35/194 (18%)
Rabgap1l	XP_006250167.1	PTB_Rab6GAP	129..257	CDD:269922	28/131 (21%)
		DUF3694	340..421	CDD:289256	18/93 (19%)
		RabGAP-TBC	541..744	CDD:278964

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910