Protein Alignment Dab and Mapk8ip1

DIOPT Version :9

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: XP_038960030.1
• Gene: Mapk8ip1 / 116457
• RGDID: 70937
• Length: 708
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 123/554 - (22%)
• Similarity: 182/554 - (32%)
• Gaps: 177/554 - (31%)

  Fly  1194 DEFNEDHDLRQIMDHQNVQTHARD-------RHGLVDSRGFPTEPS-------------SSALTV 1238
            :|| ||.||.:|.|...:....:|       |.||:.:....:..|             :::.|.
  Rat    41 EEF-EDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGSSGSAGSRLQAEMLQMDLIDAASDTP 104

  Fly  1239 GDYDEDEDAD-------AGGESSLDSNEKDAEPVSGQ---------DQYEKLSTSTQQLDAAAPA 1287
            |..|::||.|       ..|.|..:|.::.|....||         |.|.....:|..|....|.
  Rat   105 GAEDDEEDDDELAAQRPGVGPSKAESGQEPASRSQGQGQGPGTGSGDTYRPKRPTTLNLFPQVPR 169

  Fly  1288 LEDVQQLQQQSLPPKQD-QKFLSILTAP---GGGTKDDIEI---DELMHRAI------SNLSLDS 1339
            .:|.  |...||..|.. |..:|..::|   |..|.....|   |||..:..      ...|.||
  Rat   170 SQDT--LNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQGSPVPTQDRGTSTDS 232

  Fly  1340 RDRVSPATSSAAPS---RGAPG---------LHTPSQFNDVSTSPI---PLQKPGMGPS------ 1383
            ..|.:.||..|.||   ..|||         :|..:.....:|..|   |:|:| ..|:
  Rat   233 PCRRTAATQMAPPSGPPATAPGGRGHSHRDRIHYQADVRLEATEEIYLTPVQRP-PDPAEPTSTF 296

  Fly  1384 --PVPSQLSAVSQLIDTATKQMMGDK-----DREKQSWATFDSPK------AKGKARLTLPPPPP 1435
              |..|::| ||...|.|...:...:     ..|.:.:....||:      ...:..|..|||||
  Rat   297 LPPTESRMS-VSSDPDPAAYSVTAGRPHPSISEEDEGFDCLSSPEQAEPPGGGWRGSLGEPPPPP 360

  Fly  1436 PASNTSQP-----DTVE----------------SPCSSDPRDDGWSKQQRRWAKKERQQTSSSSR 1479
            .||.:|..     |:|:                .||..|..|:..|       .......:|:|
  Rat   361 RASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDS-------ATVYDNCASAS- 417

  Fly  1480 DLSPWDDETPEYLKRRQLAAAQMAHPHQPPM----QAPPQHTDRH------GYYMRHARRMNSCD 1534
              ||::....|..:.        |...:||.    .:.|...|.|      ..:|....|.:|.:
  Rat   418 --SPYESAIGEEYEE--------APQPRPPTCLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAE 472

  Fly  1535 EDYDYDGEFVARRDQPQHQQQQRKFKHGLSRSRDNFELE-----------SPSWYH--------- 1579
            .    .|.|....:..:|:|..|.....:.|..|..|||           ...||.
  Rat   473 S----FGLFSCVINGEEHEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGAR 533

  Fly  1580 --HPAHH----TWSPQE----------IEQVRVR 1597
              .||::    |..|:.          |:|.||:
  Rat   534 GVFPAYYAIEVTKEPEHMAALAKNSDWIDQFRVK 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926
Mapk8ip1	XP_038960030.1	PHA03247	186..>357	CDD:223021	39/172 (23%)
		SH3_JIP1	489..543	CDD:212876	10/53 (19%)
		PTB_JIP	560..708	CDD:269923	4/8 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334794
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840