Protein Alignment Dab and C8b

DIOPT Version :9

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: NP_598643.1
• Gene: C8b / 110382
• MGIID: 88236
• Length: 589
• Species: Mus musculus
• Alignment Length: 607
• Identity: 104/607 - (17%)
• Similarity: 186/607 - (30%)
• Gaps: 196/607 - (32%)

  Fly  1801 AVVGPQRLRKSSGSSPWDGEEPALPGQKSWKRPASAAETERRLAESRRAVALGQTPSDGE----- 1860
            |.:|......|.|..|...|..|:.|.....||.             |:||....|.|.|
Mouse    19 ATLGCLHFPGSRGGKPDFFETKAVNGSLVKSRPV-------------RSVAEAPAPIDCELSTWS 70

  Fly  1861 --------KERRFRKKTRARSAK------DLATVGAPSASTSAPSRSSY----------GRGIRD 1901
                    :::|:|.....|.::      ||:........|:.|.||..          ||.:
Mouse    71 SWTACDPCQKKRYRHTYLLRPSQFYGELCDLSDKEVEDCVTNQPCRSQVRCEGFVCAQTGRCV-- 133

  Fly  1902 NYDYICPGQRNDDDDDDDEDYVDDEPPTDEDKFERLNRRRHEMHQRMLESERRQMERHQPPSLAK 1966
            |...:|.|. ||..|..||                .|.|      |:.::.:|:||::.  ::.:
Mouse   134 NRRLLCNGD-NDCGDQSDE----------------ANCR------RIYKNCQREMEQYW--AIDR 173

  Fly  1967 LPGQNRTRGVVANSDYGFVDSYEQTPTPTPRSNASSTGPGGLMMSGGESSAGVTSSKFNFDDGFE 2031
            |          |:....|.:::|              ||    :......||..|..:..|..|.
Mouse   174 L----------ASGINLFTNTFE--------------GP----VLDHRYYAGGCSPHYILDTNFR 210

  Fly  2032 SDFNQSSPPPAPAGTASSCNSTPAGPVSANANNGGSKSLFRFSNDFSDREKREQFEMDTPPTSTP 2096
            ..:|..|..|.                        :|..:.|:  .::.|....||
Mouse   211 KPYNVESYTPQ------------------------TKCEYEFT--LTEYESYSDFE--------- 240

  Fly  2097 PITQKLRFDDNVKVSQFDDAAFEDDFAKASFDFEKEQAGSATAGAGGSGAMSRKQNM--RTSKLQ 2159
                :|..:....:..|......|.........|..:         |...::|.:..  ..||..
Mouse   241 ----RLVIEKKTHMFNFTSGFKVDGVMDLGIKVESNE---------GKNYVTRTKRFAHTQSKFL 292

  Fly  2160 QRQELIK------KSESVNIFAKKQEDPFEDDEFFKSPDQEQAMDQHND---------DTE---G 2206
            ..:.:::      ||.|:.:.       :|..:..||...|.:..::.|         .||   |
Mouse   293 HARSVLEVAHYKLKSRSLMLH-------YEFLQRVKSLPLEYSYGEYRDLLRDFGTHFITEAVLG 350

  Fly  2207 GKFQWSEDANFAKFDE-NMXFDQLFAKASGQRPDPDIDNHNYAEIDVVNDTDFSFLANLNHYYQQ 2270
            |.::::...|....:: :. ...:.|.|.|......:....|.::.|........:..:|...::
Mouse   351 GIYEYTLIMNKDAMEQGDYTLSHVTACAGGSFGIGGMVYKVYVKVGVSAKKCSDIMKEINERNKR 415

  Fly  2271 QRL---------HSLRQSLNRHVYCNLPVQQLQEQVNQPMKKSIATSTSPWHEPKVKSKPLQQLL 2326
            ..:         ....:.:....|..||..:|.|.....:|.:.|..       |:|::||.:|:
Mouse   416 STMVEDLVVLVRGGTSEDITALAYKELPTPELMEAWGDAVKYNPAII-------KIKAEPLYELV 473

  Fly  2327 -------RKPKKWKLKRTLDDF 2341
                   ....|..||:.|::|
Mouse   474 TATDFAYSSTVKQNLKKALEEF 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926
C8b	NP_598643.1	TSP1	67..115	CDD:214559	6/47 (13%)
		Ldl_recept_a	119..154	CDD:278486	10/53 (19%)
		MACPF	291..496	CDD:214671	36/219 (16%)
		TSP1	547..589	CDD:214559
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	570..589

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3535
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900