Protein Alignment Dab and mapk8ip1a

DIOPT Version :9

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: NP_001338595.1
• Gene: mapk8ip1a / 100537717
• ZFINID: ZDB-GENE-101025-1
• Length: 759
• Species: Danio rerio
• Alignment Length: 669
• Identity: 138/669 - (20%)
• Similarity: 223/669 - (33%)
• Gaps: 223/669 - (33%)

  Fly  1172 AIATDTQPE--------KEKDLLQDFPEFSDEFNEDHDLRQIMDHQNVQTHARDRHGLVDSRGFP 1228
            ::|.|::.|        .||.|..|..  .||: ||.||.::       |...|.:|
Zfish     4 SLAMDSREEWDGWMEEQWEKWLTHDIS--LDEY-EDDDLSEV-------TEITDENG-------- 50

  Fly  1229 TEPSSSALTVGDYDEDEDADAGGESSLDSNEKDAEPVSGQDQYEKLSTSTQQLDAAAPALEDVQQ 1293
                   :|:...|            ||:.:....|.:|.              |.:....:..:
Zfish    51 -------ITLVHLD------------LDTQDHMTRPTNGA--------------ARSGRRREAVE 82

  Fly  1294 LQQQSLPPKQDQKFLSILTAPGGGTKDDIEIDELMHRAISNLSLDSRDRVSPATSSAAPSRGAPG 1358
            ||.:.|       .|.::.|.||..:::.: |.....||.:...:.|        .|.|....|.
Zfish    83 LQAEML-------HLDLIDAEGGIQEEERD-DRRPFDAIDDNHKEER--------GAGPPVILPQ 131

  Fly  1359 LHTPSQFNDVSTSPIPLQKPGMGPSPVPSQLSAVSQL---IDTATKQMMGDKDREKQSWATFDSP 1420
            |.|.:..||:.|     .:|..     |:.|:...|:   .||......|:|:|.|:......||
Zfish   132 LKTLTPANDMDT-----YRPKR-----PTTLNLFPQVPRTQDTINNNSFGEKERRKEKKTHSSSP 186

  Fly  1421 KAKGKARLTLPPPPPPASNTSQPDTVESPCSSDPRDDGWSKQQRRWAKKERQQ------------ 1473
            ..||.:     ...|...:.:..|.|::...:.||... |.:.:..|.:.:||
Zfish   187 HIKGDS-----AAKPEQGSLTDGDKVQARADTKPRGPA-STKNKASAFQNKQQDKLSESLNNPTV 245

  Fly  1474 ----TSSSSRDLSPWDDETP---------EYLKRRQLAAAQMAHPHQPPMQAPPQH-------TD 1518
                |.::.||.|   .|.|         ...|.:  |.....:.::..:|.|.::       .|
Zfish   246 VAPLTQTAMRDKS---TEVPLIEGVLDISTICKEK--ARYHTVNGYREQVQYPAENEGMCDQLVD 305

  Fly  1519 RHGYYMRHARRMNSCDEDYDYDGEFVARRDQPQHQQQQRKFKHGLSRSRD------NFELESPSW 1577
            |:..|  |....|:.:|.:          ..|.:.:|:|.|   ||:|.|      :.:.|.|..
Zfish   306 RNKDY--HISEGNATEEIH----------LTPVNGEQERPF---LSQSSDSNRMSISSDTELPPL 355

  Fly  1578 YHHPAHHTWSPQEIEQVRVRSFDRTAYERSSYGPPPPIYDKRGQLRGKYRGDHRDRERERDRDRE 1642
            :::|:....:|...|:..|            |.|.||.   |.....:..||          ..:
Zfish   356 HYYPSAGCPNPSISEEDEV------------YPPTPPC---RTVSLSEQPGD----------SSQ 395

  Fly  1643 YRDYARPSYDFDYENVYEERGGRSPLAYKPGRGGGDY---LYDRERDRDRERDRKSFDRESLESY 1704
            :.:..:|....|      |.|....:|......|..|   .|....|...:.:..|. ::..:.|
Zfish   396 WAETRKPKMAKD------ETGNVKAVAVSTDASGLTYDSVKYTLVVDEHAKLELVSI-KDCYKGY 453

  Fly  1705 ESATRRRRSFGSGNDVYGSLDSRDDYRGDRERDRERDREQMKTRSLRKPT----------TTS-- 1757
            ||        .|.|.||.|....||  .|:|.|.|  .|:...||:|:.|          |||
Zfish   454 ES--------DSDNTVYESAIDEDD--EDQEADEE--DEESGARSMRRDTSCLSADSTTDTTSDV 506

  Fly  1758 ------------GKLRISG 1764
                        |:.|.||
Zfish   507 PRSRKFMNIFGNGRSRFSG 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926
mapk8ip1a	NP_001338595.1	SH3_JIP1	543..597	CDD:212876
		PTB_JIP	611..759	CDD:269923

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574011
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930