Protein Alignment Dab and dab2

DIOPT Version :9

• Sequence 1: NP_001163455.2
• Gene: Dab / 39866
• FlyBaseID: FBgn0000414
• Length: 2360
• Species: Drosophila melanogaster
• Sequence 2: XP_012823268.1
• Gene: dab2 / 100485591
• XenbaseID: XB-GENE-992286
• Length: 819
• Species: Xenopus tropicalis
• Alignment Length: 1028
• Identity: 242/1028 - (23%)
• Similarity: 365/1028 - (35%)
• Gaps: 357/1028 - (34%)

  Fly    43 RFFGDGVQFKAKLIGILEVGEARGDRMCQEALQDLK---MAIRAAGEHKQRITIHVTIDGLRLRD 104
            ||.||||::|||||||.:|.|||||:|.|:::..||   :|.|:.|:|||||.:::::.|:::.|
 Frog    43 RFKGDGVRYKAKLIGIDDVPEARGDKMSQDSMMKLKGMAVAARSQGQHKQRIWVNISLSGIKIID 107

  Fly   105 EKTGDSLYHHPVHKISFIAQDMTDSRAFGYIFGSPDSGHRFFGIKTDKAASQVVLAMRDLFQVVF 169
            ||||...:.|||:||||||:|:||:|||||:.|: :..|:||.|||.:.|..:|:.::|||||::
 Frog   108 EKTGVIEHEHPVNKISFIARDVTDNRAFGYVCGA-EGQHQFFAIKTAQQAEPLVVDLKDLFQVIY 171

  Fly   170 ELKKKEIEMARQQIQGKSLHDHSSQLASLSSLKSSGLGGMGLGHSDLASGGISSGHALTLLGSSL 234
            .:||:|.|       .|...|.|||
 Frog   172 NIKKREDE-------DKKRSDESSQ---------------------------------------- 189

  Fly   235 STTNGTSRLGVSLDVAKASGSAAKEVSPESVADLVDLEQELTSLQRGISQMERITPNEPTTSSTG 299
                           ...:||.|          |:::.:|:..|:.|:.||
 Frog   190 ---------------PLENGSDA----------LLNINEEVDKLKLGVDQM-------------- 215

  Fly   300 GAGHPSLAKSASEDDPFGDSFIYVPSYSILPPPPDSGRNRHKPPNKTPDAVTSLDAMLSPPPGTS 364
                          :.|||          :..|||    .|.|.......:..|:.
 Frog   216 --------------NLFGD----------MSTPPD----LHSPTESNEILLVDLNT--------- 243

  Fly   365 SSHGSASAGLQAADNDDDNWLQELDQQNDVFDTSKVVSSSGLGSVLAMAPL--ASSESTATPTQQ 427
                                  |:|...:....:..:|:   |.:.|.:||  ...:|..:|
 Frog   244 ----------------------EIDTNQNCVKGNPFLSN---GFISACSPLPHPQPQSPFSP--- 280

  Fly   428 LTEVAAGSGPLADLDIGLSTALGNEEQTSTILSL------DAFTDLDPLGTGRTRPY---VDKKY 483
                                    |:..|..||.      |.|.| ||.......||   :|...
 Frog   281 ------------------------EKPFSANLSFFPTPNPDPFCD-DPFTATDQSPYSSPLDSSK 320

  Fly   484 FFQELKNPPKKLLKELSSGSQAG--LGLGLSLGQLDGLFPEDSTTISTTTTTATNITAGNPQQNS 546
            |...|    |:.|..|.:||:..  |...:..||   .|.:.|.. |......::.....|.|:.
 Frog   321 FINHL----KENLSSLENGSEKNGVLTNDIEFGQ---KFDQISNH-SGKQDAKSDHWPFKPNQSL 377

  Fly   547 ANTLTSTASTAASL-GQLLSTVALNPDPLPAPISIPTS----ISHSITPSAELKLLLGHVTNPPN 606
            ....|........| |.|:|       |.|.|.:..|:    :.:.|..:::.     :|::.|:
 Frog   378 PRARTHNGGLEHRLNGPLIS-------PPPNPFAEGTAKGVDLQNGIRRNSDT-----NVSHKPD 430

  Fly   607 PTGHYYTTEPPTLNSLENPHPPADPVLL---PRDTDPFSPTRK-KSDPDPFQESDLFAKLDAFEF 667
            |           :|||     |.||:.:   |:.|.|....|. |:..|....||:|..    ..
 Frog   431 P-----------VNSL-----PCDPIAIIPPPQSTKPGRGRRSAKATSDDLFGSDIFPS----NS 475

  Fly   668 EAPPAV-------PAPSIP----NLATETKANVFNGPLQVQLPPEKELQLQQPPSTVRNRPTAS- 720
            |..|||       |||:.|    |.:..:.|....|.|.|.....::...|   |.|.|:|:|:
 Frog   476 EPAPAVGPTAQPAPAPTNPLDLFNTSGHSSATGSLGALTVNSSHAQQWNTQ---SLVFNQPSATL 537

  Fly   721 ----VSALPSGGALDVISSIS----NK----------KMPHLFGQARSF------GKSGSDIGSS 761
                :...|.....:|:.|.|    |:          :.|.|:.|..|.      .:.|.:....
 Frog   538 HTPVLGVQPGFSQPNVLGSASMTSWNQPPGLIASPPMQNPSLWNQPVSIQPNVWPQQGGLNNPFQ 602

  Fly   762 VNMRRLQESDSLSETEAAPEPPPRPDSTPYSEP----PPLPPKKQFSDLVIRPSPANTTQPPTSG 822
            |||             .||.||..|.:...|.|    ||.||.        ||:|...:....|.
 Frog   603 VNM-------------FAPRPPVLPSALTSSGPALTSPPQPPP--------RPAPQKESPKKESD 646

  Fly   823 RYEYLNSNVTARRTASSVDAPPIPLPSRRVGRSDGCFPGPGRPRKPGHTEDDYLAPLGAPPPLLP 887
            .:..|:                 ||..:........|             .||  .|..||.:
 Frog   647 AFTALD-----------------PLGEKEKKSVKDMF-------------KDY--QLTKPPAV-- 677

  Fly   888 PPSQGSSARARPQRQASLGRPQDIYENKAEILQAQA--------QAQAQ---APEVAPSSNTLAP 941
            |..:|.  ..:....:|.|...:.:.||..|.|..|        |..::   .|:.||...||..
 Frog   678 PARRGE--HQQNSNSSSTGAFNNYFTNKVGIPQDSADHDDFDINQLSSRINDPPKPAPRIQTLPM 740

  Fly   942 DITLTQLL--TLGMDDLAIKLNVPASKLSTMTLVQLTAYLSEYLSSEKSQVHS 992
            ......|.  ..|.|......|.|.:|.....:.::.|.|:|  :|....|:|
 Frog   741 SKPAEGLFENPFGSDSFTSLQNSPWTKQQAKNIQKILASLNE--TSHPFPVYS 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926	72/140 (51%)
dab2	XP_012823268.1	PTB_Dab	36..182	CDD:269926	72/146 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	127	1.000	Domainoid score	I5299
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002247
OrthoInspector	1	1.000	-	-		otm48567
Panther	1	1.100	-	-	LDO	PTHR11232
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.100