DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dab and LOC100361087

DIOPT Version :9

Sequence 1:	NP_001163455.2	Gene:	Dab / 39866	FlyBaseID:	FBgn0000414	Length:	2360	Species:	Drosophila melanogaster
Sequence 2:	NP_001177388.1	Gene:	LOC100361087 / 100361087	RGDID:	2320873	Length:	292	Species:	Rattus norvegicus

Alignment Length:	245	Identity:	56/245 - (22%)
Similarity:	81/245 - (33%)	Gaps:	63/245 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 ISSGHALTLLGSSLSTTNGTSRLGVSLDVAKASGSAAKEVSPESVADLVDLEQELTSLQRGISQM 285
            :.|.|:...|          ||.|....:...||      .|......|...|.|.:|.:.:...
  Rat    35 LQSSHSFPHL----------SRPGAPGTITPGSG------EPGGPGLRVGSSQHLRNLGKAVGAK 83

  Fly   286 ERITPNEPTTSSTGGAGHPSLAKSASEDDPFGDSFIYVP----------SYSILPPPPDSGRNRH 340
            .........:||.|..|...:.|:|....|.|:.....|          ::.:|.|||...|.|
  Rat    84 VNDLLRRKESSSLGSVGVMEINKTAEAQMPGGEDAACGPWLEDERSVQEAFPLLDPPPPITRKR- 147

  Fly   341 KPPNKTPDAV-TSLDAMLSPPP-------GTSSSHGSASAGLQAADNDDDNWLQELDQQNDVFDT 397
                 ||.|: |:.|.::|..|       ||..|.|.|        .|.....|.:..     ||
  Rat   148 -----TPRALKTTQDMLISSQPVLSNLEYGTELSPGQA--------QDSPPTAQPVSA-----DT 194

  Fly   398 SKVVSSSGL---------GSVLAMAP-LASSESTATPTQQLTEVAAGSGP 437
            |:..|::|:         |.|..:.| |....|.....::.||....|.|
  Rat   195 SRPESTTGMGEKGEALPNGEVSLLVPDLIHKNSQEESKRKATEGRKSSSP 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dab	NP_001163455.2	PTB_Dab	35..181	CDD:269926
LOC100361087	NP_001177388.1	DUF4628	23..292	CDD:292069	56/245 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334828
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840