Protein Alignment Lasp and ABP1

DIOPT Version :9

• Sequence 1: NP_730192.2
• Gene: Lasp / 39864
• FlyBaseID: FBgn0063485
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_010012.1
• Gene: ABP1 / 850450
• SGDID: S000000684
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 612
• Identity: 109/612 - (17%)
• Similarity: 216/612 - (35%)
• Gaps: 147/612 - (24%)

  Fly    76 ENTKIQSNVKYHADFEKA-----KGKFTQV-ADDPETLRIKQNTKHISNVAYHGDLEKKAAMEKQ 134
            ::..:::...:.|:|...     ||...|| |.|.:.|...:....|||.|  |.........||
Yeast    89 DSAPLKTRASFAANFAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAA--GARYSIQTSSKQ 151

  Fly   135 RGSAEVSDSSNESEYFSEQLAAEQFSQYAPTASPIPPAATTLHQQQQQLQHQQQQQYQQHQQQLQ 199
            :|.|........   |:...:....|:..|..:|.|..|..:..:..  .:.....:.:
Yeast   152 QGKASTPPVKKS---FTPSKSPAPVSKKEPVKTPSPAPAAKISSRVN--DNNDDDDWNE------ 205

  Fly   200 QQQHQHQHYLQQQQQTLPPPPIQHQQYNTAAITP---TYQQLQQQQQQQQQQRAQQQQLHDPYAH 261
                               |.::.:.::.|.:.|   :|:.:  .:...|:..|:::...||..
Yeast   206 -------------------PELKERDFDQAPLKPNQSSYKPI--GKIDLQKVIAEEKAKEDPRL- 248

  Fly   262 YQQPQALRQQQQQQQQQQQQLLQQQAIKQASHLYPTATSQQQQMPPPQSPANPQQQALNSY-NEM 325
            .|:|.| ...:.........|..:..:|:.|.......:.:.......|..|...:.:..: ||.
Yeast   249 VQKPTA-AGSKIDPSSDIANLKNESKLKRDSEFNSFLGTTKPPSMTESSLKNDDDKVIKGFRNEK 312

  Fly   326 RSAIL---QNSHHPSGNSVDQYDQPQQQ--QHQPQQQ-------STNPTLVAAQQQQSHHSLLNN 378
            ..|.|   :.:...|||:..:.:.|:.:  :.:|:.:       |....|.|:::::..
Yeast   313 SPAQLWAERKAKQNSGNAETKAEAPKPEVPEDEPEGEPDVKDLKSKFEGLAASEKEEEE------ 371

  Fly   379 NASNGGISHSHHSNINNNGHGSQNQMLPPQMRRSAASVVAYDGNSKQQVAAGPGAAQNHLQQLYA 443
                                 .:|:..||. ::|..::::....||.|   .|..|:...|   .
Yeast   372 ---------------------MENKFAPPP-KKSEPTIISPKPFSKPQ---EPVKAEEAEQ---P 408

  Fly   444 SPNYAAVTPSENSINVKQHASNGHMPNQQQQHVAGGSNIGKIADYDPLTD--GPRVVPNAGRSST 506
            ..:|..:......::::  |.|...|.:...            |:|...|  ....:|:...:|.
Yeast   409 KTDYKKIGNPLPGMHIE--ADNEEEPEENDD------------DWDDDEDEAAQPPLPSRNVASG 459

  Fly   507 TLVYSSEPRGNQGGNSVYPKRIGSVSDIDPANGIYGSLTA--AEQAHQQQKHQQYYQQVQMMQQQ 569
            ..|...||...:...|: |.|              .|:.|  .|:|.:|...::..::.:....|
Yeast   460 APVQKEEPEQEEIAPSL-PSR--------------NSIPAPKQEEAPEQAPEEEIEEEAEEAAPQ 509

  Fly   570 ---------EHPPQQQQMRQQPSYSSLQEKQSRQSTAMRVYRAIYDYEAQDVDEVSFREGDVIFE 625
                     ..||::....::|       |::..:||.      |||:|.:.:|::|.|.|.|..
Yeast   510 LPSRSSAAPPPPPRRATPEKKP-------KENPWATAE------YDYDAAEDNELTFVENDKIIN 561

  Fly   626 VESIDSGWMTGRVERTGKTGMLPANYV 652
            :|.:|..|..|.:|:.|..|:.|:|||
Yeast   562 IEFVDDDWWLGELEKDGSKGLFPSNYV 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lasp	NP_730192.2	LIM_LASP	5..57	CDD:188831
		Nebulin	68..94	CDD:279252	2/22 (9%)
		NEBU	97..127	CDD:128523	10/30 (33%)
		SH3_Nebulin_family_C	600..654	CDD:212723	20/53 (38%)
ABP1	NP_010012.1	ADF_drebrin_like	6..141	CDD:200437	13/53 (25%)
		PTZ00108	<148..404	CDD:240271	47/320 (15%)
		SH3_Abp1_fungi_C2	536..590	CDD:212894	22/59 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.864974	Normalized mean entropy	S3370
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004734
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R73
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.940