Protein Alignment Lasp and neb

DIOPT Version :10

• Sequence 1: NP_730192.2
• Gene: Lasp / 39864
• FlyBaseID: FBgn0063485
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_073768769.1
• Gene: neb / 566928
• ZFINID: ZDB-GENE-041111-216
• Length: 6327
• Species: Danio rerio
• Alignment Length: 653
• Identity: 139/653 - (21%)
• Similarity: 246/653 - (37%)
• Gaps: 199/653 - (30%)

  Fly    40 NMKTYKGYNKMPYCEAHIPKAKATAIADTPELKRIAENTKIQSNVKYHADFEKAKGKFTQVADDP 104
            |:.:.|.|.:    ||....:....:.||||::|:.||.|..|.::|..|.:|:|||.:.|.:.|
Zfish  5833 NIVSQKKYKE----EAEKTMSHYVPVLDTPEMQRVRENQKNFSTLQYQIDLKKSKGKVSAVQNTP 5893

  Fly   105 ETLRIKQNTKHISNVAYHGDLEKKAA------MEKQRGSAEVSDSSNESEYFSEQLAAEQFSQYA 163
            |.||:|:|||:.|::.|..:|.:..|      ||:.:.:.|...:....:..|:.::.
Zfish  5894 EMLRVKENTKNFSSIQYKEELGQGTAISETPEMERVKRNQEAISTIKYKDSLSQGISI------- 5951

  Fly   164 PTASPIPPAATTLHQQQQQL----------------QHQQQQQYQQHQQQLQQQQHQHQHYLQQQ 212
                |..|....:.:.|:.:                :..:.::.:::||.:...:::..   ..|
Zfish  5952 ----PDLPEVKRVRETQKNISLIHYKEDLGGGTAISETPEMERVKRNQQNISTIKYRDS---LGQ 6009

  Fly   213 QQTLPPPPIQHQQYNTAAITPTYQQLQQQQQQQQQQRAQQQQLHDPYAHYQQ------PQALRQQ 271
            ...:|..|                         :.:|.::.|.|.....|:.      |.....:
Zfish  6010 GTAMPDLP-------------------------EMKRVKENQKHISSVLYKDLSAKGTPVVFTPE 6049

  Fly   272 QQQQQQQQQQLLQQQAIKQASHLYPTATSQQQQMPPPQSPANPQQQALNSYNEMRSAILQNSHHP 336
            .::.::.|..:        :|.||..:..:|.|.........|:.:.:.....:.|.:   .:|
Zfish  6050 MERVKRNQLHI--------SSVLYSDSFRKQVQGKAAFVLDTPEMRRVKETQRIISGV---KYH- 6102

  Fly   337 SGNSVDQYDQPQQQQHQPQQQSTNPTLVAAQQQQSHHSLLNNNASNGGISHSHHSNINNNGHGSQ 401
                         |..:..:.|..||:.....::     :..|..:       .|:||.  .|.|
Zfish  6103 -------------QDFEKSKGSFTPTISDPVTER-----VKRNTQD-------FSDINY--RGIQ 6140

  Fly   402 NQMLPPQMRRSAASVVAYDGNSKQQVAAGPGAAQNHLQQLYASPNYAAVTPSENSINVKQHASNG 466
            .:::..:.:|                      |:.|.|:        .:|    .:.|.:
Zfish  6141 RRVVEMERKR----------------------AEEHDQE--------TIT----DLRVWR----- 6166

  Fly   467 HMPNQQQQHVAGGSNIGKIADYDPLTDGPRVVPNAGRSSTTLVYSSEPRGNQGGNSVYPKRIGSV 531
                         :|.|.:.||||..|..:     .||...:...::.|..:...|.  ..:..|
Zfish  6167 -------------TNPGSVFDYDPAEDNIQ-----SRSLHMMSVQAQRRSKEHSRST--SAMSGV 6211

  Fly   532 SDIDPANGIYGSLTAAEQAHQQQKHQQY-----------YQQVQMMQQQEHPPQQQQMRQQPSYS 585
            .|              |::...:...:|           |.|.:.::.|:.  ......||.:.|
Zfish  6212 GD--------------EKSEVSENVDRYSNGFAISALHGYTQTKTIEVQQR--SSSVATQQTTVS 6260

  Fly   586 SLQEKQSRQSTAMRVYRAIYDYEAQDVDEVSFREGDVIFEVESIDSGWMTGRVERTGKTGMLPAN 650
            |:   .|..||..:..||:|||.|.|.|||||::||||..|:|||.|||.|.|:|||||||||||
Zfish  6261 SV---PSHPSTTGKTVRAMYDYAAADSDEVSFKDGDVIVNVQSIDEGWMYGTVQRTGKTGMLPAN 6322

  Fly   651 YVE 653
            |||
Zfish  6323 YVE 6325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lasp	NP_730192.2	LIM_LASP	5..57	CDD:188831	5/16 (31%)
		Nebulin	67..94	CDD:459977	12/26 (46%)
		NEBU	97..127	CDD:128523	12/29 (41%)
		SH3_Nebulin_family_C	600..654	CDD:212723	39/54 (72%)
neb	XP_073768769.1	None