Protein Alignment Lasp and dbn-1

DIOPT Version :9

• Sequence 1: NP_730192.2
• Gene: Lasp / 39864
• FlyBaseID: FBgn0063485
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_499840.1
• Gene: dbn-1 / 176813
• WormBaseID: WBGene00010664
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 657
• Identity: 123/657 - (18%)
• Similarity: 226/657 - (34%)
• Gaps: 210/657 - (31%)

  Fly    57 IPKAKATAIADT----PE-LKRIAENTKIQSNVKYHADFEKAKGKFTQVADDPETLRIKQNTKHI 116
            :|.|.|.||.::    || :..:.:.|...|.:.     .:|:..|....:..|..|  |..:.:
 Worm   135 LPAANANAIVESTYSMPEKVNSVYQPTNAHSELS-----SEARENFWSTTNQEEKRR--QADEKV 192

  Fly   117 SNVAYHGDLEKKAAMEKQRGSAEVSDSSNESEYFSEQLAAEQF------SQYAPTASPIPPAATT 175
            :    |...:|:...::.|.:|.:            ...||.|      |.|.|| .|.....|.
 Worm   193 A----HAKQQKQYEADRDRTAAAI------------HTKAEDFQPEKVNSVYKPT-KPHVELKTV 240

  Fly   176 --------------LHQQQQQLQHQQ-QQQYQQHQQQLQQQQH-QHQHYLQQQQQTLPPPPIQHQ 224
                          |.|::::...:| .:|::..:|::..:.| :.::|...:..::..|...|.
 Worm   241 KREEFWSKMNEEEKLRQEEEKTAREQAHKQFEADRQRMASEIHSKTENYQPDKVTSVYKPTKPHV 305

  Fly   225 QYNTAAITPTYQQLQQQQQQQQQQRAQQQQLHDPYAHYQQPQALRQQQQQQQQQQQQLLQQQAIK 289
            :.:::|....:.::.:::|::|                       .::::.|.|:|:..:....:
 Worm   306 EISSSAREEFWSKMNEEEQRRQ-----------------------AEEKEAQAQKQKEFETDRKR 347

  Fly   290 QASHLYPTATSQQQQMPPPQSPA-----NPQQQALNSYNEMRSAILQNSHHPSG----------- 338
            .|..|:..|....:.:|...:||     .|....:.|..|:.|:      .|||
 Worm   348 IADDLHGKAQISDKPVPSSVNPAPAPAPTPSAGLVGSRKELFSS------KPSGPVLPKPQVNGS 406

  Fly   339 -------NSVDQYDQPQQQQHQPQQQST-NPTLVAAQQQQSHHSLLNNNASNGGISHSHHSNINN 395
                   .:.....:|..:..:|.:.|| .|..:|.:.:.
 Worm   407 PKKWPPVGTTSPPREPVNRLTEPDEPSTYTPKPIAYEPEP------------------------- 446

  Fly   396 NGHGSQNQMLPPQMRRSAASVVAYDGNSKQQVAAGPGAAQNHLQQLYASPNYAAVTPSENSINVK 460
                   .:..|:..:.|.|..||     ::..|.|           |.|.:.|.||
 Worm   447 -------MVYKPEAMKPAVSYDAY-----EEPPAEP-----------APPTFLAPTP-------- 480

  Fly   461 QHASNGHMPNQQQQHVAGGSNIGKIADYD--PLTDG--PRVVPNAGRSSTTLVYSS--EPRGNQG 519
            ..|.....|.....|.|        :.||  |:.:.  |.|.|.:..|.....|.:  ||..:..
 Worm   481 VIAPPPPEPTPAPSHYA--------SQYDAPPVHESFEPAVPPVSAPSHYASQYDAPPEPIDSHS 537

  Fly   520 GNSVYPKRIGSVSDIDPANGIYGSLTAAEQAHQQQKHQQYYQQVQMMQQQEHPP---QQQQMRQQ 581
            .:|..|..|.|..|:.|        ...|:.....|..........:.|.:.||   :|..|
 Worm   538 SSSQLPAHIASQYDMPP--------VMPEEPVFAPKSSPIKVAAPPIDQYDFPPAVAEQNAM--- 591

  Fly   582 PSYSSLQEKQSRQSTAMRVYRAIYDYEAQDVDEVSFREGDVIFEVESIDSGWMTGRVERTGKTGM 646
                                 |::||:|.|..|:||...|:|.:::.:||||..||.. :|:.|:
 Worm   592 ---------------------ALWDYQAADDTEISFDPDDIITDIDQVDSGWWKGRAP-SGRVGL 634

  Fly   647 LPANYVE 653
            .|||||:
 Worm   635 FPANYVK 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lasp	NP_730192.2	LIM_LASP	5..57	CDD:188831	123/657 (19%)
		Nebulin	68..94	CDD:279252	4/30 (13%)
		NEBU	97..127	CDD:128523	5/29 (17%)
		SH3_Nebulin_family_C	600..654	CDD:212723	23/54 (43%)
dbn-1	NP_499840.1	ADF_drebrin_like	3..138	CDD:200437	1/2 (50%)
		SH3	589..642	CDD:302595	24/78 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R73
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940