DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13032 and Ccdc13

DIOPT Version :9

Sequence 1:	NP_648911.1	Gene:	CG13032 / 39863	FlyBaseID:	FBgn0036652	Length:	660	Species:	Drosophila melanogaster
Sequence 2:	XP_038938679.1	Gene:	Ccdc13 / 686091	RGDID:	1586605	Length:	711	Species:	Rattus norvegicus

Alignment Length:	721	Identity:	164/721 - (22%)
Similarity:	288/721 - (39%)	Gaps:	193/721 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VVKPKPTKPESKKLRKKLSECEQEKQSLAQAIHEKNQEISDLKKSVDSLNEVLNSVPIDELRCNS 109
            :.:.:..:.|.::||.:|.|...|...|.:.:.|::.||..|||.::.          |......
  Rat    70 IFEKRVLEDEVQQLRSELRETVDENGRLYKLLKERDFEIKHLKKKIEE----------DRFAFTG 124

  Fly   110 S------IASTKILELSKKNRQMRSELEQAKSRLGKKDAQIEKLEKELRAHEEKLQHNQDLPKKG 168
            :      :.:|||:|||||||.:.:|.|.||.|:.:...:|::||.||:....|      .|.||
  Rat   125 ATGMAGDLVATKIVELSKKNRGLMAESESAKVRIKQLTNRIQELEHELQMASAK------PPAKG 183

  Fly   169 C--------------------SPD--ELQAKINSMQQKLFETRNRNTELQSQLKLAQKCLQHEIG 211
            .                    :|:  .||.::.:...|:.:.||:....:.:|::|||.|.:|:|
  Rat   184 ATDAGTKPLKTQTGDKAVQPETPEVKALQDRLAATNLKMSDLRNQIQSAKQELRVAQKVLANEVG 248

  Fly   212 ESCNI-NILANNLNQANWRGRAQQIIALNQKVHELKARLDFYEDRAVDRAEYAAPVPLGSDLELV 275
            |..|| .:||   :...||||||||:.|..||.:|:.:|...:::..  ...::.:||.||...:
  Rat   249 EDVNIQQLLA---SPGTWRGRAQQILVLQSKVRDLEKQLGQRQNKIA--GSPSSELPLNSDPRKL 308

  Fly   276 TGSCRSHHASSERLGGGDGGGATTASFDRFTPGVRKSEILHRAKVEALEK---EILSLQNQLEDQ 337
            |...::                           :.:...|.|.|.|:.||   |..:||.:||:|
  Rat   309 TAQEKN---------------------------LLRIRSLERDKQESWEKLTSERDTLQTELEEQ 346

  Fly   338 RSKTLALKVRNKNLNEEMNKYKILYNELEEQTDFNGTNINTMNDKLNQQRIQYENRLDDMRGELV 402
            :.|...::.|||.|:.|:...:.....|.|:...:...|:.:.|:|.|        |.|:.|.|.
  Rat   347 KKKFEGIRSRNKVLSSEVKTLRSQMVTLVEKGRHDDELIDALMDQLKQ--------LQDILGSLS 403

  Fly   403 RVTEERDLSRRQMEELSGMHLELQ---TVVKQKDVAMASLQDMIKKLEMDLRALSGGFL------ 458
            ...|.|..|::.:::  .::.|.|   ::|.|....:|..:..:::||:::..||..:|
  Rat   404 VQEESRRTSQQHLDQ--KVNSEAQRSSSLVAQLRAMVADREAKVRQLELEIGQLSVQYLHGKGGG 466

  Fly   459 ---------------------------------------------------------------FS 460
                                                                           ||
  Rat   467 EGASPTDARFPEDQTPITNSPASAGDHVGRLGSSRSVTSLGHTLVESALTRPSLPSPHGTSPRFS 531

  Fly   461 CREFRK------EEFVGILDALEVEKNQLMLLTKTLGDRLETERAKNEAAQEQIGKLKARISRLE 519
            ....:|      .|...:..|.|||:::|......|..|:|...:|...|:.::.:.:.|...||
  Rat   532 DSPEQKGWQAQAAEMKALWQAAEVERDRLNEFVTVLQKRVEESSSKLLEAERRLQEERQRAVLLE 596

  Fly   520 ---VKIRDLEKELDVQSDKKKRTQRMADYASSLSRTSLNGSIGSFCFENQSQYQSTNTLNSAGQP 581
               .|:| ||....:.|.|..:.:.....||    |..| |.||      ::..|::|..|....
  Rat   597 QHLEKLR-LEPSRALVSQKAPKNKPGPPAAS----TKPN-STGS------AKKDSSSTQLSDMPM 649

  Fly   582 EPRIEDLKNNLELAKEKITMLTEKLEYITEEKNADAKFFEDTINSTKTIILETVLGAREKGLSDR 646
            |.:||:|...|.:..|:..:|.:.|......|..|.:.:..|:...|.:.|:.:          |
  Rat   650 ESQIEELNARLAIQMEENGVLRDALGSALRGKEEDFRMYHQTLGQVKGVFLQAL----------R 704

  Fly   647 SKNADK 652
            .:.|:|
  Rat   705 QQKANK 710

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13032	NP_648911.1	Smc	<52..647	CDD:224117	161/707 (23%)
Ccdc13	XP_038938679.1	Smc	76..>455	CDD:224117	112/436 (26%)
Ccdc13	XP_038938679.1	SMC_prok_B	<340..>611	CDD:274008	54/281 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337520
Domainoid	1	1.000	114	1.000	Domainoid score	I5907
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I4743
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1533296at2759
OrthoFinder	1	1.000	-	-		FOG0009373
OrthoInspector	1	1.000	-	-		oto97526
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR31935
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.000