Protein Alignment Galphaf and Gnaq

DIOPT Version :9

• Sequence 1: NP_524118.1
• Gene: Galphaf / 39861
• FlyBaseID: FBgn0010223
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_112298.2
• Gene: Gnaq / 81666
• RGDID: 620770
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 396
• Identity: 136/396 - (34%)
• Similarity: 214/396 - (54%)
• Gaps: 45/396 - (11%)

  Fly     5 LLRCLRQQPAKPAAVMTHKEDQYPVSLDHHVLKDMAKGVRDT--TVKILLLGTAESGKTTIIKQM 67
            ::.|...:.||.|.           .::..:.:.:.:..||.  .:|:|||||.||||:|.||||
  Rat     6 IMACCLSEEAKEAR-----------RINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQM 59

  Fly    68 RILHINGFTDDERREKIPEIYQNIHESILQLVGQMGVLGIDFGSCTSERSADYILSLPGSAPEYM 132
            ||:|.:|::|:::|.....:||||..::..::..|..|.|.:....::..|..:..:........
  Rat    60 RIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAF 124

  Fly   133 NEEYCDHVTTLWNDVGIRACYDRSNEFPLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGI 197
            ...|.|.:.:||||.||:.||||..|:.|.||.||:|::..|::|..|:|:.:|:|..|..||||
  Rat   125 ENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPSYLPTQQDVLRVRVPTTGI 189

  Fly   198 SQITFRVPIPKSMGGGEQQFQMYDVGGQRDQRNKWIQVFEGIQAVLFLISCSEFDQNLREDPSQN 262
            .:..|.:.        ...|:|.||||||.:|.|||..||.:.:::||::.||:||.|.|..::|
  Rat   190 IEYPFDLQ--------SVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNEN 246

  Fly   263 RLQEALKLFRAVWQNRFLASAGLIVFLNKYDIMERKIRAGKHIVDYFPEYEDFCKRPQQDNCFGE 327
            |::|:..|||.:....:..::.:|:||||.|::|.||.. .|:|||||||:.    ||:|
  Rat   247 RMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMY-SHLVDYFPEYDG----PQRD----- 301

  Fly   328 SDWTKMFIKQKLVDITQEPFKRHSRNQVDLGTSERECYYHFTVATDTRCIRDVFCDVQKMILSEN 392
            :...:.||.:..||:..:              |::..|.|||.||||..||.||..|:..||..|
  Rat   302 AQAAREFILKMFVDLNPD--------------SDKIIYSHFTCATDTENIRFVFAAVKDTILQLN 352

  Fly   393 VSSMGL 398
            :....|
  Rat   353 LKEYNL 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphaf	NP_524118.1	G_alpha	30..397	CDD:214595	131/368 (36%)
		G-alpha	48..392	CDD:206639	128/343 (37%)
Gnaq	NP_112298.2	G-alpha	40..353	CDD:206639	128/344 (37%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	41..54		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	178..186		3/7 (43%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	201..210		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	270..277		5/6 (83%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	329..334		3/4 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820