Protein Alignment Galphaf and Gna12

DIOPT Version :10

• Sequence 1: NP_524118.1
• Gene: Galphaf / 39861
• FlyBaseID: FBgn0010223
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_112296.1
• Gene: Gna12 / 81663
• RGDID: 71018
• Length: 379
• Species: Rattus norvegicus
• Alignment Length: 360
• Identity: 130/360 - (36%)
• Similarity: 188/360 - (52%)
• Gaps: 46/360 - (12%)

  Fly    48 VKILLLGTAESGKTTIIKQMRILHINGFTDDERREKIPEIYQNIHESILQLVGQMGVLGIDFGSC 112
            |||||||..||||:|.:|||||:|...|......|....|:.||.:....||.....|||.:...
  Rat    56 VKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQHS 120

  Fly   113 TSERSADYILSLPGSA-----PEYMNEEYCDHVTTLWNDVGIRACYDRSNEFPLLDSAKYFLDNF 172
            .:|:...::::....|     |... :.|...::.||.|.|||..:.|.:||.|.:|.||||||.
  Rat   121 ENEKHGMFLMAFENKAGLPVEPATF-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNL 184

  Fly   173 VRISDAEYIPSTEDILHSRKITTGISQITFRV-PIPKSMGGGEQQFQMYDVGGQRDQRNKWIQVF 236
            .||....|.||.:|||.:||.|.||.:..|.: .||         |:|.||||||.||.||.|.|
  Rat   185 DRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIP---------FKMVDVGGQRSQRQKWFQCF 240

  Fly   237 EGIQAVLFLISCSEFDQNLREDPSQNRLQEALKLFRAVWQNRFLASAGLIVFLNKYDIMERKIRA 301
            :||.::||::|.||:||.|.||...|||.|::.:|..:..|:...:..:|:||||.|::..|:::
  Rat   241 DGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKS 305

  Fly   302 GKHIVDYFPEYEDFCKRPQQDNCFGESDWTKMFIKQKLVDITQ---EPFKRHSRNQVDLGTSERE 363
             ..|..:||:::            |:        ..:|.|:.:   :.|.|..||:      .:.
  Rat   306 -VSIKKHFPDFK------------GD--------PHRLEDVQRYLVQCFDRKRRNR------GKP 343

  Fly   364 CYYHFTVATDTRCIRDVFCDVQKMILSENVSSMGL 398
            .::|||.|.||..||.||..|:..||.||:..:.|
  Rat   344 LFHHFTTAIDTENIRFVFHAVKDTILQENLKDIML 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphaf	NP_524118.1	G_alpha	30..397	CDD:214595	129/357 (36%)
Gna12	NP_112296.1	G_alpha	40..377	CDD:214595	129/357 (36%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	57..70		10/12 (83%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	198..206		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	221..230		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	290..297		5/6 (83%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	349..354		2/4 (50%)