DRSC/TRiP Functional Genomics Resources

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Protein Alignment Galphaf and Gna12

DIOPT Version :9

Sequence 1:NP_524118.1 Gene:Galphaf / 39861 FlyBaseID:FBgn0010223 Length:399 Species:Drosophila melanogaster
Sequence 2:NP_112296.1 Gene:Gna12 / 81663 RGDID:71018 Length:379 Species:Rattus norvegicus


Alignment Length:360 Identity:130/360 - (36%)
Similarity:188/360 - (52%) Gaps:46/360 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 VKILLLGTAESGKTTIIKQMRILHINGFTDDERREKIPEIYQNIHESILQLVGQMGVLGIDFGSC 112
            |||||||..||||:|.:|||||:|...|......|....|:.||.:....||.....|||.:...
  Rat    56 VKILLLGAGESGKSTFLKQMRIIHGREFDQKALLEFRDTIFDNILKGSRVLVDARDKLGIPWQHS 120

  Fly   113 TSERSADYILSLPGSA-----PEYMNEEYCDHVTTLWNDVGIRACYDRSNEFPLLDSAKYFLDNF 172
            .:|:...::::....|     |... :.|...::.||.|.|||..:.|.:||.|.:|.||||||.
  Rat   121 ENEKHGMFLMAFENKAGLPVEPATF-QLYVPALSALWRDSGIREAFSRRSEFQLGESVKYFLDNL 184

  Fly   173 VRISDAEYIPSTEDILHSRKITTGISQITFRV-PIPKSMGGGEQQFQMYDVGGQRDQRNKWIQVF 236
            .||....|.||.:|||.:||.|.||.:..|.: .||         |:|.||||||.||.||.|.|
  Rat   185 DRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIP---------FKMVDVGGQRSQRQKWFQCF 240

  Fly   237 EGIQAVLFLISCSEFDQNLREDPSQNRLQEALKLFRAVWQNRFLASAGLIVFLNKYDIMERKIRA 301
            :||.::||::|.||:||.|.||...|||.|::.:|..:..|:...:..:|:||||.|::..|:::
  Rat   241 DGITSILFMVSSSEYDQVLMEDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKS 305

  Fly   302 GKHIVDYFPEYEDFCKRPQQDNCFGESDWTKMFIKQKLVDITQ---EPFKRHSRNQVDLGTSERE 363
             ..|..:||:::            |:        ..:|.|:.:   :.|.|..||:      .:.
  Rat   306 -VSIKKHFPDFK------------GD--------PHRLEDVQRYLVQCFDRKRRNR------GKP 343

  Fly   364 CYYHFTVATDTRCIRDVFCDVQKMILSENVSSMGL 398
            .::|||.|.||..||.||..|:..||.||:..:.|
  Rat   344 LFHHFTTAIDTENIRFVFHAVKDTILQENLKDIML 378

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GalphafNP_524118.1 G_alpha 30..397 CDD:214595 129/357 (36%)
G-alpha 48..392 CDD:206639 127/352 (36%)
Gna12NP_112296.1 G_alpha 40..377 CDD:214595 129/357 (36%)
G-alpha 56..373 CDD:206639 128/353 (36%)
G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 57..70 10/12 (83%)
G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 198..206 5/7 (71%)
G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 221..230 6/8 (75%)
G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 290..297 5/6 (83%)
G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230 349..354 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166345186
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0082
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D754573at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.840

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