Protein Alignment Galphaf and Gnao1

DIOPT Version :10

• Sequence 1: NP_524118.1
• Gene: Galphaf / 39861
• FlyBaseID: FBgn0010223
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_059023.1
• Gene: Gnao1 / 50664
• RGDID: 628732
• Length: 354
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 132/378 - (34%)
• Similarity: 207/378 - (54%)
• Gaps: 49/378 - (12%)

  Fly    30 SLDHHVLKDMAKGVRDTTVKILLLGTAESGKTTIIKQMRILHINGFTDDERREKIPEIYQNIHES 94
            :::.::.:|.....:|  ||:||||..||||:||:|||:|:|.:||:.::.::..|.:|.|..:|
  Rat    18 AIEKNLKEDGISAAKD--VKLLLLGAGESGKSTIVKQMKIIHEDGFSGEDVKQYKPVVYSNTIQS 80

  Fly    95 ILQLVGQMGVLGIDFGSCTSERSA------DYILSLPGSAPEYMNEEYCDHVTTLWNDVGIRACY 153
            :..:|..|..||:::|.  .||.|      |.:..:..:.|  .:.|....:..||.|.||:.|:
  Rat    81 LAAIVRAMDTLGVEYGD--KERKADSKMVCDVVSRMEDTEP--FSAELLSAMMRLWGDSGIQECF 141

  Fly   154 DRSNEFPLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGI--SQITFRVPIPKSMGGGEQQ 216
            :||.|:.|.|||||:||:..||..|:|.|:.:|||.:|..||||  :..||:          ...
  Rat   142 NRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFK----------NLH 196

  Fly   217 FQMYDVGGQRDQRNKWIQVFEGIQAVLFLISCSEFDQNLREDPSQNRLQEALKLFRAVWQNRFLA 281
            |:::||||||.:|.|||..||.:.|::|.::.|.:||.|.||.:.||:.|:|.||.::..|:|..
  Rat   197 FRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFI 261

  Fly   282 SAGLIVFLNKYDIMERKIRAGKHIVDYFPEYEDFCKRPQQDNCFGESDWTKMFIKQKLVDITQEP 346
            ...:|:||||.|:...||:... :...||||..       .|.:.::   ..:|:      ||..
  Rat   262 DTSIILFLNKKDLFGEKIKKSP-LTICFPEYPG-------SNTYEDA---AAYIQ------TQFE 309

  Fly   347 FKRHSRNQVDLGTSERECYYHFTVATDTRCIRDVFCDVQKMILSENVSSMGLF 399
            .|..|.|        :|.|.|.|.||||..|:.||..|..:|::.|:...||:
  Rat   310 SKNRSPN--------KEIYCHMTCATDTNNIQVVFDAVTDIIIANNLRGCGLY 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphaf	NP_524118.1	G_alpha	30..397	CDD:214595	130/374 (35%)
Gnao1	NP_059023.1	G-alpha	34..348	CDD:206639	127/352 (36%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		9/12 (75%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	174..182		4/7 (57%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	197..206		5/8 (63%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	266..273		5/6 (83%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		3/4 (75%)