DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphaf and gnao1b

DIOPT Version :9

Sequence 1:	NP_524118.1	Gene:	Galphaf / 39861	FlyBaseID:	FBgn0010223	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_957122.1	Gene:	gnao1b / 393801	ZFINID:	ZDB-GENE-040426-1693	Length:	354	Species:	Danio rerio

Alignment Length:	374	Identity:	126/374 - (33%)
Similarity:	200/374 - (53%)	Gaps:	41/374 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SLDHHVLKDMAKGVRDTTVKILLLGTAESGKTTIIKQMRILHINGFTDDERREKIPEIYQNIHES 94
            :::.::.:|.....:|  ||:||||..||||:||:|||:|:|.:||:.|:.::..|.:|.|..:|
Zfish    18 AIEKNLKEDGISAAKD--VKLLLLGGGESGKSTIVKQMKIIHEDGFSGDDVKQFKPVVYSNTIQS 80

  Fly    95 ILQLVGQMGVLGIDFGSCTSERSADYILSLPGSAPEYMNEEYCDHVTT----LWNDVGIRACYDR 155
            :..::..|..|||::........|..:..:.|...:  .|.|...:..    ||.|.|.:||::|
Zfish    81 LSAILRAMETLGIEYSDKDRLADAKMVFDVVGRMED--TEPYSTELLAAMIRLWTDTGTQACFNR 143

  Fly   156 SNEFPLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGISQITFRVPIPKSMGGGEQQFQMY 220
            |.|:.|.|||:|:||:..||...:|:|:.:|||.:|..||||.:..|..   |::     .|:::
Zfish   144 SREYQLNDSAQYYLDSLQRIGSPDYLPTEQDILRTRVKTTGIVETHFSF---KNL-----NFRLF 200

  Fly   221 DVGGQRDQRNKWIQVFEGIQAVLFLISCSEFDQNLREDPSQNRLQEALKLFRAVWQNRFLASAGL 285
            ||||||.:|.|||..||.:.|::|.::.|.:||.|.||.:.||:.|:|.||.::..|:|.....:
Zfish   201 DVGGQRSERKKWIHCFEDVTAIIFCVAMSGYDQMLHEDETTNRMHESLMLFDSICNNKFFVDTSI 265

  Fly   286 IVFLNKYDIMERKIRAGKHIVDYFPEYEDFCKRPQQDNCFGESDWTKMFIKQKLVDITQEPFKRH 350
            |:||||.|:...|| ....:...||||..       .|.|           :......|..|:..
Zfish   266 ILFLNKKDLFGEKI-VKSPLSICFPEYTG-------PNTF-----------EAAASYIQGQFETK 311

  Fly   351 SRNQVDLGTSERECYYHFTVATDTRCIRDVFCDVQKMILSENVSSMGLF 399
            :|      :..:|.|.|.|.||||..|:.||..|..:|::.|:...||:
Zfish   312 NR------SPNKEIYCHLTCATDTGNIQVVFDAVTDIIIANNLRGCGLY 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphaf	NP_524118.1	G_alpha	30..397	CDD:214595	124/370 (34%)
Galphaf	NP_524118.1	G-alpha	48..392	CDD:206639	121/347 (35%)
gnao1b	NP_957122.1	G_alpha	14..352	CDD:214595	124/370 (34%)
gnao1b	NP_957122.1	G-alpha	43..348	CDD:206639	115/339 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820