DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphaf and gna13b

DIOPT Version :9

Sequence 1:	NP_524118.1	Gene:	Galphaf / 39861	FlyBaseID:	FBgn0010223	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001013281.2	Gene:	gna13b / 336333	ZFINID:	ZDB-GENE-030131-8277	Length:	377	Species:	Danio rerio

Alignment Length:	377	Identity:	136/377 - (36%)
Similarity:	205/377 - (54%)	Gaps:	43/377 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LDHHVLKDMAKGVRDTTVKILLLGTAESGKTTIIKQMRILHINGFTDDERREKIPEIYQNIHESI 95
            :|..:.|:  |......|||||||..||||:|.:|||||:|.:.|...::.|....||.|:.:.:
Zfish    34 IDREIFKE--KTFVKRLVKILLLGAGESGKSTFLKQMRIIHGDDFDKGDKEEFRGTIYSNVMKGV 96

  Fly    96 LQLVGQMGVLGIDFGSCTSERSADYILSL--------PGSAPEYMNEEYCDHVTTLWNDVGIRAC 152
            ..||.....|.|.:|:.:::..||.:::.        .|.....:..:|...:..||.|:||:..
Zfish    97 RVLVDAREKLHIPWGNPSNQTHADIMMAFDTRSTMVSQGMLETKLFPQYLPSIRALWADIGIQHA 161

  Fly   153 YDRSNEFPLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGISQITFRVP-IPKSMGGGEQQ 216
            |||..||.|.:|.||||||..::...:|:|:.:|||.:||.|.||.:..|.:. :|
Zfish   162 YDRRREFQLGESVKYFLDNLDKLGAPDYLPTQQDILLARKPTKGIHEYDFEIKNVP--------- 217

  Fly   217 FQMYDVGGQRDQRNKWIQVFEGIQAVLFLISCSEFDQNLREDPSQNRLQEALKLFRAVWQNRFLA 281
            |:|.||||||.:|.:|.:.||.:.::|||:|.||:||.|.||...|||.|:|.:|..:..||...
Zfish   218 FKMVDVGGQRSERRRWFECFESVTSILFLVSSSEYDQVLMEDRQTNRLMESLNIFETIVNNRVFN 282

  Fly   282 SAGLIVFLNKYDIMERKIRAGKHIVDYFPEYEDFCKRPQQDNCFGESDWTKMFIKQKLVDITQEP 346
            :..:|:||||.|::|.|::: ..|.|||||:.|      ...|.|:       :|..||    |.
Zfish   283 NVSIILFLNKTDLLEEKVKS-VSIQDYFPEFTD------DPWCLGD-------VKNFLV----EC 329

  Fly   347 FKRHSRNQVDLGTSERECYYHFTVATDTRCIRDVFCDVQKMILSENVSSMGL 398
            |:...|:|     .::..|:|||.|.:|..||.||.||:..||.:|:..:.|
Zfish   330 FRNKRRDQ-----QQKPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLML 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphaf	NP_524118.1	G_alpha	30..397	CDD:214595	135/374 (36%)
Galphaf	NP_524118.1	G-alpha	48..392	CDD:206639	131/352 (37%)
gna13b	NP_001013281.2	G_alpha	29..375	CDD:214595	135/374 (36%)
gna13b	NP_001013281.2	G-alpha	49..371	CDD:206639	131/353 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.750