Protein Alignment Galphaf and GNAZ

DIOPT Version :10

• Sequence 1: NP_524118.1
• Gene: Galphaf / 39861
• FlyBaseID: FBgn0010223
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: XP_047297302.1
• Gene: GNAZ / 2781
• HGNCID: 4395
• Length: 393
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 105/310 - (33%)
• Similarity: 164/310 - (52%)
• Gaps: 49/310 - (15%)

  Fly     8 CLRQQPAKPAAVMTHKEDQYPVSLDHHVLKDMAKGVRDTTVKILLLGTAESGKTTIIKQMRILHI 72
            |.:....|.||..:.:       :|.|:..:..:..|:  :|:|||||:.|||:||:|||:|:|.
Human     3 CRQSSEEKEAARRSRR-------IDRHLRSESQRQRRE--IKLLLLGTSNSGKSTIVKQMKIIHS 58

  Fly    73 NGFTDDERREKIPEIYQNIHESILQLVGQMGVLGIDFGSCTSERSAD----YILSLPGSAPEYMN 133
            .||..:..:|..|.|..|..:|:.:::..:..|.|||.:  .:|:.|    :.|:.|..:...:.
Human    59 GGFNLEACKEYKPLIIYNAIDSLTRIIRALAALRIDFHN--PDRAYDAVQLFALTGPAESKGEIT 121

  Fly   134 EEYCDHVTTLWNDVGIRACYDRSNEFPLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGI- 197
            .|....:..||.|.|.:||:.||:|:.|.|:|.|:|::..||:.|:|||:.||||.||.:||||
Human   122 PELLGVMRRLWADPGAQACFSRSSEYHLEDNAAYYLNDLERIAAADYIPTVEDILRSRDMTTGIV 186

  Fly   198 -SQITFRVPIPKSMGGGEQQFQMYDVGGQRDQRNKWIQVFEGIQAVLFLISCSEFDQNLRED--- 258
             ::.||:          |..|:|.||||||.:|.|||..|||:.|::|.:..|.:|..|.||
Human   187 ENKFTFK----------ELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQT 241

  Fly   259 -----PSQNRLQEALKLFRAVWQNRFLASAGLIVFLNKYDIMERKIRAGK 303
                 .||.|....||          ..:.|    .|...|:.|::|:|:
Human   242 GSGELGSQTRASCFLK----------AQTPG----YNTSKILRRELRSGQ 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Galphaf	NP_524118.1	G_alpha	30..397	CDD:214595	101/288 (35%)
GNAZ	XP_047297302.1	G_alpha	13..>241	CDD:214595	91/248 (37%)