DRSC/TRiP Functional Genomics Resources

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Protein Alignment Galphaf and Gnas

DIOPT Version :9

Sequence 1:NP_524118.1 Gene:Galphaf / 39861 FlyBaseID:FBgn0010223 Length:399 Species:Drosophila melanogaster
Sequence 2:XP_038960221.1 Gene:Gnas / 24896 RGDID:2716 Length:1145 Species:Rattus norvegicus


Alignment Length:375 Identity:145/375 - (38%)
Similarity:212/375 - (56%) Gaps:53/375 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 TVKILLLGTAESGKTTIIKQMRILHINGFTDD----------------ERREKIPEIYQNIHESI 95
            |.::||||..||||:||:|||||||:|||..:                |:..|:.:|..|:.|:|
  Rat   790 THRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSDGSEKATKVQDIKNNLKEAI 854

  Fly    96 LQLVGQMG--VLGIDFGSCTSERSADYILSLPGSAPEY-MNEEYCDHVTTLWNDVGIRACYDRSN 157
            ..:|..|.  |..::..:..::...|||||:. :.|.: ...|:.:|...||.|.|:||||:|||
  Rat   855 ETIVAAMSNLVPPVELANPENQFRVDYILSVM-NVPNFDFPPEFYEHAKALWEDEGVRACYERSN 918

  Fly   158 EFPLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGISQITFRVPIPKSMGGGEQQFQMYDV 222
            |:.|:|.|:||||....|..|:|:||.:|:|..|.:|:||.:..|:|        .:..|.|:||
  Rat   919 EYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQV--------DKVNFHMFDV 975

  Fly   223 GGQRDQRNKWIQVFEGIQAVLFLISCSEFDQNLREDPSQNRLQEALKLFRAVWQNRFLASAGLIV 287
            |||||:|.||||.|..:.|::|:::.|.::..:|||...|||||||.||:::|.||:|.:..:|:
  Rat   976 GGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVIL 1040

  Fly   288 FLNKYDIMERKIRAGK-HIVDYFPEY------EDFCKRPQQDNCFGESDWTKMFIKQKLVDITQE 345
            ||||.|::..|:.||| .|.|||||:      ||....|.:|.....:   |.||:.:.:.|:..
  Rat  1041 FLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRA---KYFIRDEFLRISTA 1102

  Fly   346 PFKRHSRNQVDLGTSERECYYHFTVATDTRCIRDVFCD----VQKMILSE 391
            .           |.....||.|||.|.||..||.||.|    :|:|.|.:
  Rat  1103 S-----------GDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ 1141

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GalphafNP_524118.1 G_alpha 30..397 CDD:214595 145/375 (39%)
G-alpha 48..392 CDD:206639 144/374 (39%)
GnasXP_038960221.1 PHA03247 <122..560 CDD:223021
UDM1_RNF168_RNF169-like 741..>783 CDD:409016
G-alpha 791..1139 CDD:206639 143/370 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D325067at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10218
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
44.020

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