DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Galphaf and egl-30

DIOPT Version :9

Sequence 1:	NP_524118.1	Gene:	Galphaf / 39861	FlyBaseID:	FBgn0010223	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_740789.1	Gene:	egl-30 / 171751	WormBaseID:	WBGene00001196	Length:	355	Species:	Caenorhabditis elegans

Alignment Length:	394	Identity:	139/394 - (35%)
Similarity:	212/394 - (53%)	Gaps:	46/394 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CLRQQPAKPAAVMTHKEDQYPVSLDHHVLKDMAKGVRDTTVKILLLGTAESGKTTIIKQMRILHI 72
            ||.::..:...:....|.|        :.:|.....|:  :|:|||||.||||:|.||||||:|.
Worm     4 CLSEEAREQKRINQEIEKQ--------LQRDKRNARRE--LKLLLLGTGESGKSTFIKQMRIIHG 58

  Fly    73 NGFTDDERREKIPEIYQNIHESILQLVGQMGVLGIDFGSCTSE--RSADYILSLPGSAPEYMNEE 135
            .|::::::|..|..:|||:..:|..::..|..|.|.||:.:.|  ..|..:..:...:.....|.
Worm    59 QGYSEEDKRAHIRLVYQNVFMAIQSMIRAMDTLDIKFGNESEELQEKAAVVREVDFESVTSFEEP 123

  Fly   136 YCDHVTTLWNDVGIRACYDRSNEFPLLDSAKYFLDNFVRISDAEYIPSTEDILHSRKITTGISQI 200
            |..::..||.|.||:.||||..|:.|.|||||:|.:..|::..:|:|:.:|||..|..||||.:.
Worm   124 YVSYIKELWEDSGIQECYDRRREYQLTDSAKYYLSDLRRLAVPDYLPTEQDILRVRVPTTGIIEY 188

  Fly   201 TFRVPIPKSMGGGEQ-QFQMYDVGGQRDQRNKWIQVFEGIQAVLFLISCSEFDQNLREDPSQNRL 264
            .|.:         || .|:|.||||||.:|.|||..||.:.:::||::.||:||.|.|..::||:
Worm   189 PFDL---------EQIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVECDNENRM 244

  Fly   265 QEALKLFRAVWQNRFLASAGLIVFLNKYDIMERKIRAGKHIVDYFPEYEDFCKRPQQDNCFGESD 329
            :|:..|||.:....:..::.:|:||||.|::|.|| ...|:.||||||:.    |.:|.......
Worm   245 EESKALFRTIITYPWFTNSSVILFLNKKDLLEEKI-LYSHLADYFPEYDG----PPRDPIAAREF 304

  Fly   330 WTKMFIKQKLVDITQEPFKRHSRNQVDLGTSERECYYHFTVATDTRCIRDVFCDVQKMILSENVS 394
            ..|||     ||:..:              :::..|.|||.||||..||.||..|:..||..|:.
Worm   305 ILKMF-----VDLNPD--------------ADKIIYSHFTCATDTENIRFVFAAVKDTILQHNLK 350

  Fly   395 SMGL 398
            ...|
Worm   351 EYNL 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Galphaf	NP_524118.1	G_alpha	30..397	CDD:214595	134/369 (36%)
Galphaf	NP_524118.1	G-alpha	48..392	CDD:206639	131/346 (38%)
egl-30	NP_740789.1	G_alpha	13..353	CDD:214595	136/382 (36%)
egl-30	NP_740789.1	G-alpha	34..349	CDD:206639	131/347 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920