DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Baldspot and ELOVL1

DIOPT Version :9

Sequence 1:	NP_648909.1	Gene:	Baldspot / 39860	FlyBaseID:	FBgn0260960	Length:	316	Species:	Drosophila melanogaster
Sequence 2:	NP_001243328.1	Gene:	ELOVL1 / 64834	HGNCID:	14418	Length:	279	Species:	Homo sapiens

Alignment Length:	294	Identity:	78/294 - (26%)
Similarity:	130/294 - (44%)	Gaps:	98/294 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 TWVFYYCGIYMLVIFGGQHFMQNRPRFQLRGPLIIWN-TLLAM-------FSIMGAART------ 86
            |:|::       |:..|...|.||..|||||.:|::| :|:|:       |.:.|...|
Human    37 TYVYF-------VLSLGPRIMANRKPFQLRGFMIVYNFSLVALSLYIVYEFLMSGWLSTYTWRCD 94

  Fly    87 ------APELIHVLRHYGLFHSVCVPSYIEQDRVCGFWTWLFVLSKLPELGDTIFIVLRKQ--PL 143
                  :||.:.::|                      ..|||:.||..||.||:..:|||:  .:
Human    95 PVDYSNSPEALRMVR----------------------VAWLFLFSKFIELMDTVIFILRKKDGQV 137

  Fly   144 IFLHWYHHITVLIYSWFSYTEYTSSARWFI------------VMNYCVHSVMYSYYALKAARFNP 196
            .|||.:|| :||.:||:          |.:            ::|..||.:||.||.|.|  |.|
Human   138 TFLHVFHH-SVLPWSWW----------WGVKIAPGGMGSFHAMINSSVHVIMYLYYGLSA--FGP 189

  Fly   197 PR----FISMIITSLQLAQMIIGCAINVWANGFLKTHGTSSCHISQRNINLSIAMYSS-YFVLFA 256
            ..    :....:|::||.|.:: .::::....|:     |||:.....|...|.||.: :|:||:
Human   190 VAQPYLWWKKHMTAIQLIQFVL-VSLHISQYYFM-----SSCNYQYPVIIHLIWMYGTIFFMLFS 248

  Fly   257 RFFYKAYLAPGGHKSRRMAASLAAQNVVKQSSSP 290
            .|:|.:|.     |.:|:..:|      :|:.:|
Human   249 NFWYHSYT-----KGKRLPRAL------QQNGAP 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Baldspot	NP_648909.1	ELO	30..271	CDD:395916	73/273 (27%)
ELOVL1	NP_001243328.1	ELO	23..260	CDD:307345	74/275 (27%)
ELOVL1	NP_001243328.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03201	275..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820