DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mo25 and Cab39l

DIOPT Version :9

Sequence 1:	NP_001261958.1	Gene:	Mo25 / 39858	FlyBaseID:	FBgn0017572	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001347520.1	Gene:	Cab39l / 69008	MGIID:	1914081	Length:	337	Species:	Mus musculus

Alignment Length:	334	Identity:	218/334 - (65%)
Similarity:	277/334 - (82%)	Gaps:	4/334 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPLFGKSQKSPVELVKSLKEAINALEAGDRKVEKAQEDVSKNLVSIKNMLYGSSDAEPPADYVVA 65
            ||||.||.|:|.|:||.||:.:..||..|:|.:||.|:|||:|.::|.:|.|::|.|||.: .||
Mouse     4 MPLFSKSHKNPAEIVKILKDNLAILEKQDKKTDKASEEVSKSLQAMKEILCGTNDKEPPTE-AVA 67

  Fly    66 QLSQELYNSNLLLLLIQNLHRIDFEGKKHVALIFNNVLRRQIGTRSPTVEYICTKPEILFTLMAG 130
            ||:||||:|.||:.||.:|..|||||||.|..||||:||||||||.||||||.:.|.|||.|:.|
Mouse    68 QLAQELYSSGLLVTLIADLQLIDFEGKKDVTQIFNNILRRQIGTRCPTVEYISSHPHILFMLLKG 132

  Fly   131 YEDAHPEIALNSGTMLRECARYEALAKIMLHSDEFFKFFRYVEVSTFDIASDAFSTFKELLTRHK 195
            ||  .|:|||..|.|||||.|:|.||||:|.|::|..||:|||:||||||||||:|||:||||||
Mouse   133 YE--APQIALRCGIMLRECIRHEPLAKIILFSNQFRDFFKYVELSTFDIASDAFATFKDLLTRHK 195

  Fly   196 LLCAEFLDANYDKFFSQHYQRLLNSENYVTRRQSLKLLGELLLDRHNFTVMTRYISEPENLKLMM 260
            :|.|:||:.|||..| :.|::||.||||||:||||||||||:|||||||:||:|||:||||||||
Mouse   196 VLVADFLEQNYDTIF-EDYEKLLQSENYVTKRQSLKLLGELILDRHNFTIMTKYISKPENLKLMM 259

  Fly   261 NMLKEKSRNIQFEAFHVFKVFVANPNKPKPILDILLRNQTKLVDFLTNFHTDRSEDEQFNDEKAY 325
            |:|::||.|||||||||||||||:|:|.:||::|||:||.||::||::|..:|::||||.|||.|
Mouse   260 NLLRDKSPNIQFEAFHVFKVFVASPHKTQPIVEILLKNQPKLIEFLSSFQKERTDDEQFADEKNY 324

  Fly   326 LIKQIKELK 334
            |||||::||
Mouse   325 LIKQIRDLK 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mo25	NP_001261958.1	Mo25	3..334	CDD:400746	214/330 (65%)
Cab39l	NP_001347520.1	Mo25	6..333	CDD:400746	214/330 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837169
Domainoid	1	1.000	469	1.000	Domainoid score	I454
eggNOG	1	0.900	-	-		E1_KOG1566
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	469	1.000	Inparanoid score	I1506
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54315
OrthoDB	1	1.010	-	-		D509368at33208
OrthoFinder	1	1.000	-	-		FOG0001165
OrthoInspector	1	1.000	-	-		otm42365
orthoMCL	1	0.900	-	-		OOG6_101307
Panther	1	1.100	-	-	LDO	PTHR10182
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R936
SonicParanoid	1	1.000	-	-		X720
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.800