DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mo25 and cab39

DIOPT Version :9

Sequence 1:	NP_001261958.1	Gene:	Mo25 / 39858	FlyBaseID:	FBgn0017572	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_001002145.1	Gene:	cab39 / 415235	ZFINID:	ZDB-GENE-040625-158	Length:	341	Species:	Danio rerio

Alignment Length:	343	Identity:	232/343 - (67%)
Similarity:	288/343 - (83%)	Gaps:	9/343 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPL-FGKSQKSPVELVKSLKEAINALE---AGDRKVEKAQEDVSKNLVSIKNMLYGSSDAEPPAD 61
            ||. |.||.|.|.::||:||:.:..||   ..|:|.|||.|:|||:|:|:|.:|||:::.||..:
Zfish     1 MPFPFVKSHKCPADIVKNLKDNMTILEKQDISDKKAEKASEEVSKSLLSMKEILYGTNEKEPQTE 65

  Fly    62 YVVAQLSQELYNSNLLLLLIQNLHRIDFEGKKHVALIFNNVLRRQIGTRSPTVEYICTKPEILFT 126
             .||||:||||||.||..|:.:|..|||||||.||.|||::||||||||:|||||:||:..|||.
Zfish    66 -AVAQLAQELYNSGLLSTLVADLQLIDFEGKKDVAQIFNDILRRQIGTRTPTVEYLCTQQNILFM 129

  Fly   127 LMAGYEDAHPEIALNSGTMLRECARYEALAKIMLHSDEFFKFFRYVEVSTFDIASDAFSTFKELL 191
            |:.|||.  |:||||.|.|||||.|:|.||||.|.|::|:.||||||:||||||||||:|||:||
Zfish   130 LLKGYES--PDIALNCGIMLRECIRHEPLAKITLCSEQFYDFFRYVEMSTFDIASDAFATFKDLL 192

  Fly   192 TRHKLLCAEFLDANYDKFFSQHYQRLLNSENYVTRRQSLKLLGELLLDRHNFTVMTRYISEPENL 256
            ||||:|.||||:.:||:|||: |::||:||||||:||||||||||||||||||:||:|||:||||
Zfish   193 TRHKVLSAEFLEQHYDRFFSE-YEKLLHSENYVTKRQSLKLLGELLLDRHNFTIMTKYISKPENL 256

  Fly   257 KLMMNMLKEKSRNIQFEAFHVFKVFVANPNKPKPILDILLRNQTKLVDFLTNFHTDRSEDEQFND 321
            |||||:|::||||||||||||||||||||||..|||||||:|||||::||:.|..||:|||||:|
Zfish   257 KLMMNLLRDKSRNIQFEAFHVFKVFVANPNKTPPILDILLKNQTKLIEFLSKFQNDRAEDEQFSD 321

  Fly   322 EKAYLIKQIKELK-PLPE 338
            ||.||||||::|| |.|:
Zfish   322 EKTYLIKQIRDLKRPTPQ 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mo25	NP_001261958.1	Mo25	3..334	CDD:400746	226/334 (68%)
cab39	NP_001002145.1	Mo25	5..334	CDD:285738	226/332 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580744
Domainoid	1	1.000	463	1.000	Domainoid score	I455
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69212
Inparanoid	1	1.050	468	1.000	Inparanoid score	I1494
OMA	1	1.010	-	-		QHG54315
OrthoDB	1	1.010	-	-		D509368at33208
OrthoFinder	1	1.000	-	-		FOG0001165
OrthoInspector	1	1.000	-	-		otm24399
orthoMCL	1	0.900	-	-		OOG6_101307
Panther	1	1.100	-	-	O	PTHR10182
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R936
SonicParanoid	1	1.000	-	-		X720
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.900