DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mo25 and mop-25.2

DIOPT Version :9

Sequence 1:	NP_001261958.1	Gene:	Mo25 / 39858	FlyBaseID:	FBgn0017572	Length:	339	Species:	Drosophila melanogaster
Sequence 2:	NP_496092.1	Gene:	mop-25.2 / 174527	WormBaseID:	WBGene00013140	Length:	338	Species:	Caenorhabditis elegans

Alignment Length:	338	Identity:	209/338 - (61%)
Similarity:	270/338 - (79%)	Gaps:	9/338 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PLFGKSQKSPVELVKSLKEAINALE-----AGDRKVEKAQEDVSKNLVSIKNMLYGSSDAEPPAD 61
            |||||:.|:|.::||:|::|:..::     ..:||||||.|:.:|.|...|..:|| |||..|.:
Worm     4 PLFGKADKTPADVVKNLRDALLVIDRHGTNTSERKVEKAIEETAKMLALAKTFIYG-SDANEPNN 67

  Fly    62 YVVAQLSQELYNSNLLLLLIQNLHRIDFEGKKHVALIFNNVLRRQIGTRSPTVEYICTKPEILFT 126
            ..|.||:||:||:|:|.:||::||:.:||.||.||.:|||:||||||||||||||:..:||||.|
Worm    68 EQVTQLAQEVYNANVLPMLIKHLHKFEFECKKDVASVFNNLLRRQIGTRSPTVEYLAARPEILIT 132

  Fly   127 LMAGYEDAHPEIALNSGTMLRECARYEALAKIMLHSDEFFKFFRYVEVSTFDIASDAFSTFKELL 191
            |:.|||  .|:|||..|:||||..|:|.||:|:|:|:.|.:||.:|:...||||:|||||||:|:
Worm   133 LLLGYE--QPDIALTCGSMLREAVRHEHLARIVLYSEYFQRFFVFVQSDVFDIATDAFSTFKDLM 195

  Fly   192 TRHKLLCAEFLDANYDKFFSQHYQRLLNSENYVTRRQSLKLLGELLLDRHNFTVMTRYISEPENL 256
            |:||.:|||:||.|||:||.| |..|.|||||||||||||||||||||||||:.|.:||:.||||
Worm   196 TKHKNMCAEYLDNNYDRFFGQ-YSALTNSENYVTRRQSLKLLGELLLDRHNFSTMNKYITSPENL 259

  Fly   257 KLMMNMLKEKSRNIQFEAFHVFKVFVANPNKPKPILDILLRNQTKLVDFLTNFHTDRSEDEQFND 321
            |.:|.:|::|.||||:|||||||:||||||||:||.|||.||:.|||:|||.||.||:.||||||
Worm   260 KTVMELLRDKRRNIQYEAFHVFKIFVANPNKPRPITDILTRNRDKLVEFLTAFHNDRTNDEQFND 324

  Fly   322 EKAYLIKQIKELK 334
            |||||||||:||:
Worm   325 EKAYLIKQIQELR 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mo25	NP_001261958.1	Mo25	3..334	CDD:400746	207/335 (62%)
mop-25.2	NP_496092.1	Mo25	5..336	CDD:285738	206/334 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159371
Domainoid	1	1.000	423	1.000	Domainoid score	I315
eggNOG	1	0.900	-	-		E1_KOG1566
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69212
Inparanoid	1	1.050	426	1.000	Inparanoid score	I972
Isobase	1	0.950	-	0	Normalized mean entropy	S694
OMA	1	1.010	-	-		QHG54315
OrthoDB	1	1.010	-	-		D509368at33208
OrthoFinder	1	1.000	-	-		FOG0001165
OrthoInspector	1	1.000	-	-		otm14664
orthoMCL	1	0.900	-	-		OOG6_101307
Panther	1	1.100	-	-	O	PTHR10182
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R936
SonicParanoid	1	1.000	-	-		X720
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790