Protein Alignment CG4101 and Manbal

DIOPT Version :10

• Sequence 1: NP_648908.1
• Gene: CG4101 / 39857
• FlyBaseID: FBgn0025558
• Length: 87
• Species: Drosophila melanogaster
• Sequence 2: NP_081244.2
• Gene: Manbal / 69161
• MGIID: 1916411
• Length: 85
• Species: Mus musculus
• Alignment Length: 800
• Identity: 165/800 - (20%)
• Similarity: 315/800 - (39%)
• Gaps: 195/800 - (24%)

  Fly    80 EVKEAFDGLGLELENSRKKMIELEDRIRISALE-----AEKLEELQKQSASELEEKLKIS----D 135
            |.|..|.|..:    .|:..|.||.:: ||.:|     :|| ::|...|...|...:..|    .
Mouse  1424 EQKPTFTGRSI----IRRINITLEGQV-ISPVEPKSNGSEK-KDLSSSSGLGLNGSVTTSQTAAS 1482

  Fly   136 ERYSKTD-------------------ALLSQALSQNSVLEQKLKSLEELSEKVSELKSALIVAEE 181
            :.|:.:|                   |.|....||.| .:..|:..||...:...:|....|:..
Mouse  1483 DSYNNSDSTMLTPPSSPPPPPPREEPACLQNKKSQVS-WDNLLEGTEEPKSETMPIKPRTPVSPP 1546

  Fly   182 EGKKSSIQMQEYQEKVS-------KLESSLNQSSARNSELE--EDLRIALQKGAEHEDIGNVSTK 237
            :.|:..:.......:.:       |..:...:...|.|.:|  :::..|       :|:.:....
Mouse  1547 QPKQKPVTAPVPTPRTNPPVVMRVKEPNKPRREEVRKSFVECVDEIPFA-------DDVEDTYDD 1604

  Fly   238 RSVELQGLFQTSQLKLEKAEEKLKDLEAIQVKNSSLEATLSVAMEKERDLSENLNAVMEKLKSSE 302
            |:.:..||            ||.......:|........|::|||..:   .|:..|....|.|
Mouse  1605 RTPDASGL------------EKFYTPPTSKVNRDKPPLHLALAMENGK---PNIPGVSRTAKGS- 1653

  Fly   303 ERLEKQAREIDEATTRSIELEALHKHSELKVQKTMEDFSSRDTEAKSLTEKSKDLEEKIRVYEGK 367
            :....:|:||.|...|:.|             |:::..:.:|..||.|| |.||.|    |.:|.
Mouse  1654 QHFSPEAKEIAEERMRARE-------------KSVKSQALKDAMAKQLT-KMKDSE----VAKGA 1700

  Fly   368 LA-------EACGQSLSLQEELDQSSA----ENELLADT----------NNQLKIKIQELEGYL- 410
            :|       |..|:| ..|.:..:.||    |::..|||          :..|...:...|...
Mouse  1701 VAKVAWDIPETKGKS-KKQSKAQKDSAVKALESKKQADTLPDRFFSTPSSKALDSSVTSSESSTG 1764

  Fly   411 -DSEKETAI--EKLNQKDTEAKDLITKLKSHENVIEEHKRQVLEA--SGVADTRKVEVEEALLKL 470
             .|:|.:::  .:.|:|:.:||:  .:|.|.|....:|| .:.:|  ||....:|.:.:::....
Mouse  1765 GKSKKRSSLFSPRKNKKEKKAKN--ERLSSTEETPPKHK-SLWKAVFSGYKKDKKKKDDKSCPST 1826

  Fly   471 NTLESTIEELEKENGDL-AEVNIKLNQKLANQGSETDDFQAKLSVLEAEKYQQAKELQITIEDLT 534
            .:..:|.:..:|::..| ...:::|.:.|:  .||..|.... .|||....:...:..:.:.||.
Mouse  1827 PSSSTTGDSGKKKDSPLDRSSDLRLRRNLS--FSEDSDLSCD-DVLERSSQKSKGDRHVDLFDLV 1888

  Fly   535 KQLTSE-------------RERLRSQISSLEEEKNQVNEIYQSTKNELVKLQAQLQVDKSKSDDM 586
            ..|..|             |.:.|.:::...:|:::..|..:..|.::||:: .::.:|.|.::
Mouse  1889 SDLKKEAIKEEKAKEKAKDRAKERGRVTEKGKERSRERENEKRVKEKMVKMK-DVEREKGKEEE- 1951

  Fly   587 VSQIEKLSALVAEKSVLESKFEQVEIHLKEEVEKVAELTSKLQEHKHKASDRDVLEEKAIQLHKE 651
                   |..|......:..:...:.:.:||:.  |:||.::|    ||:.|...:|:..:||:.
Mouse  1952 -------SVYVPHALAFKRSYATKKTYTEEELN--AKLTRRVQ----KAARRQAKQEELKRLHRA 2003

  Fly   652 --LQASHTAISEQKEALSHKHSELEATL------------KKSQE--ELDAKKSVIVHLESKLNE 700
              :|.....:.|::..|..:...:|..|            |..||  :|..:|:.:|..||:|..
Mouse  2004 QMIQRQLEQVEEKQRQLEERGVAVEKALRGEAGMGKKDDPKLMQEWFKLVQEKNALVRYESELMI 2068

  Fly   701 LEQKVKLADAKS----------------KETESTGKEEEV------EVKSRDSDLSFSNPKQTKI 743
            ..::::|.|.:|                |..|...:|:::      .|:.|||.::....::.:.
Mouse  2069 FARELELEDRQSRLQQELRERMAIDDHLKTEEELAEEKQILNEMLEVVEQRDSLVALLEEQRLRE 2133

  Fly   744 K---KNLDAASSSGHVMIQK 760
            |   |:|:|      ||:.|
Mouse  2134 KEEDKDLEA------VMLSK 2147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4101	NP_648908.1	UPF0239	12..86	CDD:399634	2/5 (40%)
Manbal	NP_081244.2	UPF0239	7..72	CDD:399634
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..85