DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta6 and PRE9

DIOPT Version :9

Sequence 1:	NP_524115.1	Gene:	Prosbeta6 / 39855	FlyBaseID:	FBgn0002284	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_011651.3	Gene:	PRE9 / 853036	SGDID:	S000003367	Length:	258	Species:	Saccharomyces cerevisiae

Alignment Length:	229	Identity:	59/229 - (25%)
Similarity:	96/229 - (41%)	Gaps:	45/229 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 FSP----YE--------SNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGS 74
            |||    |:        |:.|:.:.|...|..|:||:.:::|.......:..||:||:.:..:..
Yeast    13 FSPEGRLYQVEYALESISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAV 77

  Fly    75 AGCWADTLSLTGSIKVRMQSYEHTHLRTMTTEAVAQMLSIAM--YNRR--FFPYYVSNILAGIDN 135
            ||..||...|..:.::..|:|..|:...:..|.:.:.||...  |.:.  ..|:.||.|.||.|:
Yeast    78 AGLTADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDD 142

  Fly   136 EGKGVVYSYDPIGHCE--KATYRAGGT--AGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSV 196
            .....:|:.:|.|:..  ||......|  |.||||           |:.:|..|:....|.|:..
Yeast   143 RYGYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQ-----------MDYKDDMKVDDAIELALKT 196

  Fly   197 ASDTFISAAERDIYTGDSVLINIITKDGIEVRTL 230
            .|.|..|:|              :|.|.:|..|:
Yeast   197 LSKTTDSSA--------------LTYDRLEFATI 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta6	NP_524115.1	proteasome_beta_type_1	22..235	CDD:239726	59/229 (26%)
Prosbeta6	NP_524115.1	PRE1	24..225	CDD:223711	55/220 (25%)
PRE9	NP_011651.3	proteasome_alpha_type_4	4..216	CDD:239721	58/227 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810