DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta6 and PSMB10

DIOPT Version :9

Sequence 1:	NP_524115.1	Gene:	Prosbeta6 / 39855	FlyBaseID:	FBgn0002284	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_002792.1	Gene:	PSMB10 / 5699	HGNCID:	9538	Length:	273	Species:	Homo sapiens

Alignment Length:	224	Identity:	51/224 - (22%)
Similarity:	96/224 - (42%)	Gaps:	27/224 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VPGMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCW 78
            :||:|.|.   ....|.:|..:...|..::.||||.::...:..::..|:..::|:.....||..
Human    27 LPGLKVPH---ARKTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVA 88

  Fly    79 ADTLSLTGSIKVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRR-FFPYY----VSNILAGIDNEGK 138
            ||....|..:..:|:      |..::|....::.::....|: .|.|.    .|.|:.|:|..|.
Human    89 ADAEMTTRMVASKME------LHALSTGREPRVATVTRILRQTLFRYQGHVGASLIVGGVDLTGP 147

  Fly   139 GVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSVASDTFIS 203
             .:|...|.|...:..:.|.|:.......||:::. ..||.||.|..:.:          :...:
Human   148 -QLYGVHPHGSYSRLPFTALGSGQDAALAVLEDRF-QPNMTLEAAQGLLV----------EAVTA 200

  Fly   204 AAERDIYTGDSVLINIITKDGIE-VRTLT 231
            ....|:.:|.:|...:|||.|.: :|||:
Human   201 GILGDLGSGGNVDACVITKTGAKLLRTLS 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta6	NP_524115.1	proteasome_beta_type_1	22..235	CDD:239726	47/216 (22%)
Prosbeta6	NP_524115.1	PRE1	24..225	CDD:223711	43/205 (21%)
PSMB10	NP_002792.1	proteasome_beta_type_7	40..227	CDD:239732	43/204 (21%)
PSMB10	NP_002792.1	Pr_beta_C	232..267	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810