DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta6 and Psma4

DIOPT Version :9

Sequence 1:	NP_524115.1	Gene:	Prosbeta6 / 39855	FlyBaseID:	FBgn0002284	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_058977.1	Gene:	Psma4 / 29671	RGDID:	61846	Length:	261	Species:	Rattus norvegicus

Alignment Length:	231	Identity:	49/231 - (21%)
Similarity:	91/231 - (39%)	Gaps:	46/231 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 FSP----YE--------SNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRT-----QSKLFKLSPQ 69
            |||    |:        .:.|:.:.|..:|..::||:.|     |||...     ..|::||:..
  Rat    12 FSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERR-----NIHKLLDEVFFSEKIYKLNED 71

  Fly    70 TVLGSAGCWADTLSLTGSIKVRMQSYEHTHLRTMTTE-AVAQMLSIAMYNRRF---FPYYVSNIL 130
            .....||..:|...||..:::..|.|...:...:..| .|..:..|.....:|   .|:.||.:.
  Rat    72 MACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLY 136

  Fly   131 AGIDNEGKGVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVS 195
            .|.|......:|..||.|:       .||...|.:.   :|.....:|..:|..:.::|.:.|::
  Rat   137 IGWDKHYGFQLYQSDPSGN-------YGGWKATCIG---NNSAAAVSMLKQDYKEGEMTLKSALA 191

  Fly   196 VASDTFISAAERDIYTGDSVLINIITKDGIEVRTLT 231
            :|........:          ::.::.:.:|:.|||
  Rat   192 LAVKVLNKTMD----------VSKLSAEKVEIATLT 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta6	NP_524115.1	proteasome_beta_type_1	22..235	CDD:239726	49/231 (21%)
Prosbeta6	NP_524115.1	PRE1	24..225	CDD:223711	43/221 (19%)
Psma4	NP_058977.1	proteasome_alpha_type_4	3..216	CDD:239721	46/228 (20%)
Psma4	NP_058977.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	240..261
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900