DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosbeta6 and Psmb10

DIOPT Version :9

Sequence 1:	NP_524115.1	Gene:	Prosbeta6 / 39855	FlyBaseID:	FBgn0002284	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_038668.2	Gene:	Psmb10 / 19171	MGIID:	1096380	Length:	273	Species:	Mus musculus

Alignment Length:	223	Identity:	47/223 - (21%)
Similarity:	96/223 - (43%)	Gaps:	26/223 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DYQVPGMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSA 75
            ::.:||::.|.   ....|.:|..:...|..::.||||.::...:..::..|:..::|:.....|
Mouse    24 EHVLPGLRVPH---ARKTGTTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGA 85

  Fly    76 GCWADTLSLTGSIKVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRR-FFPYY----VSNILAGIDN 135
            |..|||...|.....:|:      |..::|....::.::....|: .|.|.    .|.::.|:|.
Mouse    86 GVAADTEMTTRMAASKME------LHALSTGREPRVATVTRILRQTLFRYQGHVGASLVVGGVDL 144

  Fly   136 EGKGVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSVASDT 200
            .|. .:|...|.|...:..:.|.|:.......:|:::. ..||.||.|.:: |.:.....:.|
Mouse   145 NGP-QLYEVHPHGSYSRLPFTALGSGQGAAVALLEDRF-QPNMTLEAAQEL-LVEAITAGILS-- 204

  Fly   201 FISAAERDIYTGDSVLINIITKDGIEVR 228
                   |:.:|.:|...:||..|.:::
Mouse   205 -------DLGSGGNVDACVITAGGAKLQ 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta6	NP_524115.1	proteasome_beta_type_1	22..235	CDD:239726	44/212 (21%)
Prosbeta6	NP_524115.1	PRE1	24..225	CDD:223711	43/205 (21%)
Psmb10	NP_038668.2	20S_bact_beta	39..238	CDD:163402	44/205 (21%)
		proteasome_beta_type_7	40..226	CDD:239732	43/204 (21%)
		Pr_beta_C	232..267	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810