DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4098 and NUDT9

DIOPT Version :9

Sequence 1:	NP_660192.1	Gene:	CG4098 / 39854	FlyBaseID:	FBgn0036648	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_076952.1	Gene:	NUDT9 / 53343	HGNCID:	8056	Length:	350	Species:	Homo sapiens

Alignment Length:	278	Identity:	144/278 - (51%)
Similarity:	183/278 - (65%)	Gaps:	9/278 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 HLMCRNNMYPRSSVLRYPVSDEQVFWSEPFPDYCPPAYTAPHI-GGQVWADPPLPSDTFWPQWNQ 102
            |...|.:.||.|.|.|..|.:|:|.|...:.||.|..|||..: .|..||||.:....|.|::|:
Human    62 HNKARTSPYPGSKVERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNFSPKFNE 126

  Fly   103 LDGQVNRESFHGAYNVQNGLPLNPIGRTGLTGRGSLGRWGPNHAADPIVTRWKRDDQGAIVANPT 167
            .||.|.|:|.:|.|.::||.|.||.|||||.|||.|||||||||||||:||||||..|..:.:|.
Human   127 KDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKRDSSGNKIMHPV 191

  Fly   168 TGKNIIQMVAIQRSDNKLWAIPGGMVDPGENVSVTLKREFTEEALNFTDKANMVER--------F 224
            :||:|:|.|||:|.|...||||||||||||.:|.||||||.|||||...|.:..:|        .
Human   192 SGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQKTSAEKREIEEKLHKL 256

  Fly   225 FQAGGVQVYQGYVDDFRNTDNAWMETTALNFHDEDGSQVGQLELMAGDDASNVRWTDVDSNLKLH 289
            |....:.:|:|||||.||||||||||.|:|:|||.|..:..|.|.|||||..|:|.|::..|||:
Human   257 FSQDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLMLEAGDDAGKVKWVDINDKLKLY 321

  Fly   290 ANHADIVREVVIRRNAHW 307
            |:|:..::.|..:|:|||
Human   322 ASHSQFIKLVAEKRDAHW 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4098	NP_660192.1	ADPRase_NUDT9	125..303	CDD:239642	105/185 (57%)
NUDT9	NP_076952.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..77		6/14 (43%)
		ADPRase_NUDT9	149..335	CDD:239642	105/185 (57%)
		Nudix box	215..237		17/21 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152972
Domainoid	1	1.000	139	1.000	Domainoid score	I4836
eggNOG	1	0.900	-	-		E1_KOG4195
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11435
Inparanoid	1	1.050	294	1.000	Inparanoid score	I2766
Isobase	1	0.950	-	0	Normalized mean entropy	S3629
OMA	1	1.010	-	-		QHG52466
OrthoDB	1	1.010	-	-		D1186086at2759
OrthoFinder	1	1.000	-	-		FOG0007217
OrthoInspector	1	1.000	-	-		oto89974
orthoMCL	1	0.900	-	-		OOG6_106760
Panther	1	1.100	-	-	LDO	PTHR13030
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5323
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.720