DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4098 and Nudt9

DIOPT Version :9

Sequence 1:	NP_660192.1	Gene:	CG4098 / 39854	FlyBaseID:	FBgn0036648	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001006992.1	Gene:	Nudt9 / 305149	RGDID:	1359522	Length:	350	Species:	Rattus norvegicus

Alignment Length:	305	Identity:	152/305 - (49%)
Similarity:	193/305 - (63%)	Gaps:	19/305 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NPLTS------AQMMSSL--VKPGIFRHLMCRNNMYPRSSVLRYPVSDEQVFWSEPFPDYCPPAY 76
            ||..|      |.:||..  ||..  .|...|.:.||.|.|.|..|.:|:|.|...:.||.|..|
  Rat    37 NPFPSCGFHLKANIMSGSNGVKDN--SHNKARTSPYPGSKVERSKVPNEKVGWLVEWQDYNPVEY 99

  Fly    77 TAPHI-GGQVWADPPLPSDTFWPQWNQLDGQVNRESFHGAYNVQNGLPLNPIGRTGLTGRGSLGR 140
            ||..: .|..||||.:...:|.|::|:.||.|.|:|.:|.|.::||.|.||.|||||.|||.|||
  Rat   100 TAVSVLAGPQWADPQISESSFSPRFNEKDGHVERKSQNGLYEIENGRPRNPAGRTGLVGRGLLGR 164

  Fly   141 WGPNHAADPIVTRWKRDDQGAIVANPTTGKNIIQMVAIQRSDNKLWAIPGGMVDPGENVSVTLKR 205
            ||||||||||:||||||:.|..:.:|.:||.|:|.|||:|.|...||||||||||||.:|.||||
  Rat   165 WGPNHAADPIITRWKRDESGNKITHPVSGKCILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKR 229

  Fly   206 EFTEEALNFTDKANMVER--------FFQAGGVQVYQGYVDDFRNTDNAWMETTALNFHDEDGSQ 262
            ||.|||||...|::..:|        .|....:.:|:|||||.||||||||||.|:|:|||.|..
  Rat   230 EFGEEALNSLQKSSAEKREIEEKLHALFSQEHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGET 294

  Fly   263 VGQLELMAGDDASNVRWTDVDSNLKLHANHADIVREVVIRRNAHW 307
            :..|.|.|||||..|:|.|:...|||:|:|:..::.|..:|:|||
  Rat   295 MDNLTLEAGDDAGKVKWVDISDQLKLYASHSQFIKLVAEKRDAHW 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4098	NP_660192.1	ADPRase_NUDT9	125..303	CDD:239642	105/185 (57%)
Nudt9	NP_001006992.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..77		8/25 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..153		15/36 (42%)
		ADPRase_NUDT9	149..335	CDD:239642	105/185 (57%)
		Nudix box	215..237		17/21 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346563
Domainoid	1	1.000	139	1.000	Domainoid score	I4677
eggNOG	1	0.900	-	-		E1_KOG4195
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11435
Inparanoid	1	1.050	296	1.000	Inparanoid score	I2658
OMA	1	1.010	-	-		QHG52466
OrthoDB	1	1.010	-	-		D1186086at2759
OrthoFinder	1	1.000	-	-		FOG0007217
OrthoInspector	1	1.000	-	-		oto97091
orthoMCL	1	0.900	-	-		OOG6_106760
Panther	1	1.100	-	-	LDO	PTHR13030
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5323
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770