DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Syx8 and STX8

DIOPT Version :9

Sequence 1:	NP_524113.1	Gene:	Syx8 / 39847	FlyBaseID:	FBgn0036643	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_004844.1	Gene:	STX8 / 9482	HGNCID:	11443	Length:	236	Species:	Homo sapiens

Alignment Length:	229	Identity:	59/229 - (25%)
Similarity:	122/229 - (53%)	Gaps:	8/229 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DSWDIEYEGCERLRHQLLVYLNQRQQLNPRTSQFVQLTSSIQTGIEQLAKDMKHLKVVLDNAITW 71
            |.|...|:...::..::...:.||.|...:..:..:||.:|:..::.|.:.:..||.:|..|::.
Human     4 DPWFSTYDSTCQIAQEIAEKIQQRNQYERKGEKAPKLTVTIRALLQNLKEKIALLKDLLLRAVST 68

  Fly    72 ETSPEEELQQRRIDWDRLTSQLREIREKFANSSRSNVPAASGSAWQDQDLGPGHSN------SSR 130
            ....:.|..:|:...|.|.::.|.:...|.|....  |....|:...::...|..|      ...
Human    69 HQITQLEGDRRQNLLDDLVTRERLLLASFKNEGAE--PDLIRSSLMSEEAKRGAPNPWLFEEPEE 131

  Fly   131 NTALDVEALKQKKTEMLAQQNEGLEVLSATLSRQRQLATQLGNEVEDQNNILDNLANAMDRVETG 195
            ...|..:.::|::.:::.:|:.||:.||:.:|||:|:..::|||:::||.|:|:|||.::..:..
Human   132 TRGLGFDEIRQQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEK 196

  Fly   196 VQRETQSIGQVNRRDSTWGYWLVIIALFVAIIVV 229
            ::.||:.:..|:|:.::.|..:||:.|.|||:||
Human   197 LRNETRRVNMVDRKSASCGMIMVILLLLVAIVVV 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx8	NP_524113.1	SNARE_Syntaxin8	147..205	CDD:277205	21/57 (37%)
STX8	NP_004844.1	SNARE_Syntaxin8	152..204	CDD:277205	20/51 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	62	1.000	Domainoid score	I10377
eggNOG	1	0.900	-	-		E1_KOG3202
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37973
Inparanoid	1	1.050	98	1.000	Inparanoid score	I5028
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54955
OrthoDB	1	1.010	-	-		D1455798at2759
OrthoFinder	1	1.000	-	-		FOG0003175
OrthoInspector	1	1.000	-	-		oto90482
orthoMCL	1	0.900	-	-		OOG6_103098
Panther	1	1.100	-	-	LDO	PTHR19957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5676
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.870