Protein Alignment Syx8 and STX10

DIOPT Version :9

• Sequence 1: NP_524113.1
• Gene: Syx8 / 39847
• FlyBaseID: FBgn0036643
• Length: 232
• Species: Drosophila melanogaster
• Sequence 2: NP_003756.1
• Gene: STX10 / 8677
• HGNCID: 11428
• Length: 249
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 47/239 - (19%)
• Similarity: 113/239 - (47%)
• Gaps: 43/239 - (17%)

  Fly    16 CERLRHQLLVYLNQRQQLNPRTSQFVQLTSSIQTGIEQLAKDMKHLK----VVLDNAITWETSPE 76
            ||.|:....|   .|::|:       ..|:.::.|:..:..|::.|:    :|..|...::. |.
Human    29 CELLQESAAV---GREELD-------WTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKL-PA 82

  Fly    77 EELQQRRIDWDRLTSQLREIREKFANSS------RSNVPAASGSAWQDQDLGPGHSNSSRNTALD 135
            .:||:|::..:|:...::|:::...:.:      |:|....:|.        |. :..|.:..||
Human    83 GDLQERKVFVERMREAVQEMKDHMVSPTAVAFLERNNREILAGK--------PA-AQKSPSDLLD 138

  Fly   136 VEAL--------KQKKTEMLA--QQNEGLEVLSATLSRQRQLATQLGNEVEDQNNILDNLANAMD 190
            ..|:        :|:.|:.|.  :|::.||::|.::...:.::.::|.|:::|..:||..|..||
Human   139 ASAVSATSRYIEEQQATQQLIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMD 203

  Fly   191 RVET---GVQRETQSIGQVNRRDSTWGYWLVIIALFVAIIVVVF 231
            ..::   ||.|:...:..:......|....|::.:.:.:::::|
Human   204 HTQSRMDGVLRKLAKVSHMTSDRRQWCAIAVLVGVLLLVLILLF 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Syx8	NP_524113.1	SNARE_Syntaxin8	147..205	CDD:277205	16/62 (26%)
STX10	NP_003756.1	Syntaxin-6_N	13..103	CDD:286286	18/84 (21%)
		SNARE_Syntaxin6	160..225	CDD:277204	15/64 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810